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Dr. Traj Nibber, PhD

Posts by: Dr. Traj Nibber, PhD

What is the Importance of Free-curcumin?

Curcumin is a well-studied herb, and as such there are thousands of different products on retailer’s shelves. Moreover, there are dozens of different brands with serious marketing dollars towards differentiating their brands and, touting their effectiveness. Curcumin belongs to a group called curcuminoids comprising three slightly different molecules that are extracted from the root or rhizomes of the Curcuma plant. Curcumin comprises over 80% of this group and is the most researched molecule, and therefore, everyone refers to curcumin when they really mean the curcuminoid group. Virtually all the products on the market consist of this curcuminoid group, and not

Pre, Pro, And Post- Biotics: strategies for IBD management

Dr Traj Nibber and Dr Anjan Nibber Our gut contains billions of live bacteria, belonging to over a 1000 different species. In fact, the bacteria in our gut are thought to outnumber the number of cells of an adult person by 10-100 fold! These bacteria, or microbiota, play a crucial role in maintaining the delicate balance in the gut or homeostasis, including the metabolism of nutrients and the production of essential vitamins (K and B12). Gut microbiota can also prevent invasion of pathogenic bacteria by outcompeting them for adherence to mucosa and epithelium (the lining of the gut wall) for

P.E.A.k Pain Relief

The endocannabinoidome (eCBome) is a broader and more appropriate term than the old endocannabinoid system (ECS), and incorporates the more recent research into this fascinating area. What is the eCBome Briefly, eCBome is a protective, and communication network that exists all over the body, and interacts with hormonal, nervous, immune, endocrine, microbiome, and other systems of the body. The eCBome plays a major role in the health and disease of many organs of the body including; the reproductive system in both males and females, hormonal system, kidneys, liver, gut microbiome, heart and circulatory system, nervous system, skin among other tissues.

The Endocannabinoid System (ECS): What Is It, What Does It Do and Why Do I Need To Know?

The endocannabinoid system (ECS) is another level of security, a defence system that the body layers onto the existing security organization that is keeping us safe, whilst making sure checks and balances are in place. The ECS is a vast signalling network that communicates with other well-known systems including the nervous, immune, hormonal or the endocrine, and other networks, but also some that are rather more obscure, like the lymphatic or the enteric nervous system sometimes called the “second brain”. The ECS’s job is relaying important and timely information between these systems, but it also primes and prepares the body

Is the intake of grapefruit juice linked to increased breast cancer risk?

The human body relies heavily on enzymes to perform all sorts of functions such as: the breakdown of various foods so that the nutrients can be absorbed, accelerating various chemical reactions which otherwise would be too slow for the requirements of the body, and generating energy quickly and efficiently among others. Then there is a whole series of enzymes whose job is to detoxify chemicals, either foreign (toxins) or ones produced by the body itself including hormones like estrogen. One such large group of enzymes is called the cytochrome P450 (CYP) family which breaks down different chemicals and thus reduces

Natural Health Products: The Hype, Promises and Lies

Do you remember coral calcium, shark cartilage, oxygen drops and structured water? These are some of the natural products (dietary supplements) that fall into the category of hype, promises and outright lies! It is amazing that this industry every now and then (more often than not) heralds a major advancement, the next big thing! How many times have you heard of the word breakthrough when it comes to natural products? It seems that this industry cannot survive without an offering of products with such exaggerated claims otherwise it fears it will go belly up, much to the disdain and exasperation

NOx Technology – A Remarkable Discovery!

Every now and then there are discoveries that can be called true paradigm shifts in nutrition. NOx technology is exactly that, a monumental paradigm shift. Nitric oxide (NO) is a small, very simple molecule made up of just two atoms, nitrogen and oxygen. After extensive research in 1998, the Nobel Prize in medicine was awarded to three researchers in elucidating the mechanism of action of NO which at the time was called endothelial relaxing factor (EFR) or relaxer of blood vessels. Since then, the research into the biology of NO has progressed with zealous fervor. NO has been shown to

Treatments for Iron Deficiency Anemia and the Need for Phytoferritin Research

KEY WORDS: Anemia: A condition defined by low levels of haemoglobin in the body. Symptoms include fatigue, heart palpitations, headaches and chest pains. Iron- deficiency anemia (IDA): A common type of anemia caused by iron deficiency due to bleeding, poor diet, or malabsorption. As iron plays a vital role in the body, IDA can lead to cognitive, motor and growth defects in children. Ferritin: A protein found in high levels in humans, animals and plants. Its principal role is to bind and sequester iron. As such, ferritin is an organic source of iron.Phytoferritin: Plant ferritin that is similar in structure

The Key to Vitamin E

Many people may not know how vitamin E works but here is what we do know: Oxidative stress can cause cell and DNA damage leading to a plethora of chronic diseases   Vitamin E has antioxidant effects and supplementation has been shown to have unique health benefits Recent research has focused on specific compounds called tocotrienols that make up part of the larger vitamin E family, as having the most potent health benefits. Let’s take a closer look… What is Oxidative Stress? Oxidative stress occurs when there is a disturbance in the balance between the production of reactive oxygen species (ROS; free

The Use of Non-Human Animals in Medical Research

The number of treatments formulated each year has increased dramatically over the last 10 years due to technological advancements within the biomedical field. However, formulation and development does not necessarily equate to launch on the market, as many treatments are deemed ineffective, inferior to those already on the market, or unsafe.  Therefore, all treatments produced by pharmaceuticals must undergo rigorous testing before being launched on the market. It would of course be premature and dangerous to immediately commence the testing of a new treatment in human subjects.  As such, scientists take to studying the effects in models, which can include

The Carrageenan Controversy: Unfounded?

Widely used in the food industry as a gelling or thickening agent, the use of carrageenan as a food additive has been heavily discussed.  In this blog Dr. Nibber will summarize what carrageenan is and will review some of the controversial and unfounded negative health effects of this food additive. What is Carrageenan? Extracted from edible seaweed, carrageenans comprise a family of sulphated polysaccharides. Due to their structure, carrageenans are highly flexible, have large molecular weights, and strong binding capabilities, making them excellent gelling and stabilizing agents.  Despite having no nutritional value, carrageenans provide an excellent alternative to gelatin, as

What Does Bioavailability Mean?

We constantly hear and read the term bioavailability thrown around in pharmacological and nutritional sciences. But what does it mean when a product has high or low bioavailability? Why is it important, and what factors contribute to this? Definition of bioavailability While there are slight differences in the usage of the term between pharmacology and nutritional sciences, bioavailability is essentially a measure of the extent and rate at which a product enters systemic circulation. Simply put, bioavailability is the amount of an ingredient that gets absorbed in the body. When products are administered intravenously, they are fully available in the blood

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