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Innovations in Research

The Mighty Molecule: The Role of PEA in the Endocannabinoid System

Definitions PEA (N-palmitoylethanolamide): An endogenous fatty acid amide synthesized and metabolized by cells that binds to cell receptors. It influences a multitude of physiological functions and has potent anti-inflammatory and pain-relieving properties. Endocannabinoid System: A lipid communication network that has critical physiological functions and serves a vital purpose for our health and well-being through signaling processes, homeostasis and hormone regulation. Lipids and the ECS In 1929, scientists George Oswald Burr and his wife, Mildred Burr, discovered that omega 6 fatty acids were essential for health. This kicked off science’s interest into lipids, and by the 1960s a new age of lipid

I take AOR’s Total E, but I am concerned about toxicity and taking too much?

The upper dosage of Vitamin E, according to the NIH is 1,500IU for a 19+ year old Male/Female. AOR’s Total E provides roughly ~400mg per softgel of a mixed tocopherol and tocotrienol blend. For information regarding the benefits of supplementing with this blend, please visit (www.aor.ca/products-page/total-e/) This is an interesting question, because I have noticed numerous new research articles that have been recently published about Vitamin E. One such study by experts at the Linus Pauling Institute at Oregon State University is titled, “Excess Vitamin E Intake Not a Health Concern”. The lead researcher, Maret Traber, an internationally recognized expert

Survive Spring Allergy Season, Naturally

Spring is (finally) in the air for most of us but, unfortunately, so is pollen, and that translates into seasonal allergies and irritating, cold-like symptoms for millions of North Americans. Also known as “hay fever,” seasonal allergies occur when outdoor moulds release spores and trees, grasses and weeds release pollen. When those of us who are allergic breathe them in, our immune systems treat them as invaders and release histamines from our “mast cells” into our bloodstream to fight them. Histamines are organic compounds involved in local immune and inflammatory responses. They defend your immune system by causing a chain

Management of Cardiovascular Disease

WITH ANKASCIN – CLINICAL RESEARCH The key findings relevant to the use of Ankascin red yeast rice to manage blood cholesterol came from an experimental study in hamsters. Unlike other animals commonly used in research, hamsters develop many of the key characteristics of human cardiovascular disease when fed a diet that is high in fats and sugar15. The positive effects of monascin and ankaflavin in animal models led to human clinical trials to evaluate the ability of these molecules to manage blood cholesterol, blood pressure, and blood sugar. STUDY MONASCIN AND ANKAFLAVIN ACT AS NOVEL HYPOLIPIDEMIC AND HIGH-DENSITY LIPOPROTEIN CHOLESTEROL-RAISING

NOx Technology – A Remarkable Discovery!

Every now and then there are discoveries that can be called true paradigm shifts in nutrition. NOx technology is exactly that, a monumental paradigm shift. Nitric oxide (NO) is a small, very simple molecule made up of just two atoms, nitrogen and oxygen. After extensive research in 1998, the Nobel Prize in medicine was awarded to three researchers in elucidating the mechanism of action of NO which at the time was called endothelial relaxing factor (EFR) or relaxer of blood vessels. Since then, the research into the biology of NO has progressed with zealous fervor. NO has been shown to

A New Kind of Genetic Testing: Nutrigenomics

The scientific community has known for some time that different people respond differently than others to similar environments, and this is also the case with nutrition. After all, we’ve all heard a friend say that a particular diet worked wonders for them, but when we try the same program, we don’t see the same success. Wouldn’t it be great if there were a way to know whether your genetic blueprint was compatible with a particular diet or exercise regimen? Or whether you have specific sensitivities to certain foods? And what if you could understand your genetic susceptibility to stress or

Personalized Nutrition: Achieving Optimal Health through Genetic Testing

Over the decades, authorities have published public dietary and nutritional guidelines in an attempt to inform individuals about the healthiest choices to optimize health and prevent disease. However, conflicting and sometimes contradictory messaging has often led to more confusion than clarity. With so many different types of diets and supplements available it is difficult to know if they are really right for you. We have all heard some people say that certain diets work wonders for them but unfortunately not all see the same success.  Part of the reason there are wide variations in individual responses to different diets and

Probiotics – Not all are created equal

Probiotics, defined as ‘live microorganisms, which when administered in adequate amounts, confer a health benefit on the host’, are finally becoming an option for gastroenterologists in Canada, after being available for many years in Japan, Europe and the United States of America. Unfortunately, Health Canada and the US Food and Drug Administration have not controlled the use of the term ‘probiotic’ or put into place United Nations and World Health Organization guidelines. The net result is that a plethora of products called ‘probiotics’ are available that are not truly probiotic. This situation can be confusing for consumers, and even some

Vitamin B12: There is More Than One

Vitamin B is actually a group, or complex, of several vitamins, each of which is known by their specific number or name. Vitamin B12, aka cobalamin, is one of this group that can itself be broken into four different types: Methylcobalamin, Hydroxocobalamin, Adenosylcobalamin, and Cyanocobalamin. Except for Cyanocobalamin, which is synthetic, they are naturally found in animal products, including fish, meat, poultry, eggs and milk products. They are essential for overall health and vitality, and they contribute in different ways. Although each cobalamin performs unique functions, they are often interrelated. A deficiency in any one of them can lead to

Protein: The Importance of Fuelling our Muscles After Exercise

There is a special feeling associated with conquering a challenging workout. As part of an active daily lifestyle, it is healthy to safely test our body’s boundaries of strength and endurance. This challenge is different for everyone; attempting more weight or repetitions at the gym, extending your long run by a few extra kilometres, or holding onto those new yoga poses as long as possible. Overcoming these new obstacles not only leaves us with a great sense of accomplishment but also feeling very sore the next day! To reduce muscle soreness and improve muscle function for further training, a proper

Grape Extract: Not Just the Seed

Those familiar with the science of nutritional supplements have also heard of the antioxidant capabilities of grape seed extract. However, the phytonutrient value of the grape does not begin and end with the seed. In fact, the polyphenolic content of the skin is at least equal to that found in the seed. Further, the diversity of each of the respective polyphenolic sources is such that they each perform distinctively specific tasks. Studies have shown that the synergy between the polyphenols of the skin and seed of the grape is superior, by demonstrating that the combination of polyphenols from both sources

VeinHealth Pro™

The case for a cost effective and safer alternative for Deep Vein Thrombosis Approximately 60,000-100,000 Americans die each year of deep vein thrombosis (DVT, also called venous thromboembolism). Blood clots form in the deep veins of the legs, then travel through the bloodstream to the lungs, where they can cause sudden death by pulmonary embolism (PE, i.e. a blockage of the pulmonary artery). About 10-30% of patients with DVT die within one month of diagnosis and sudden death is the first symptom in about 25% of people who have PE. In people who have had DVT, approximately 50% will have