{"id":5101,"date":"2023-05-11T12:53:56","date_gmt":"2023-05-11T19:53:56","guid":{"rendered":"https:\/\/aor.ca\/?post_type=ingredients&p=5101"},"modified":"2025-10-31T14:23:07","modified_gmt":"2025-10-31T21:23:07","slug":"bio-three-enterococcus-faecium-t-110","status":"publish","type":"ingredients","link":"https:\/\/aor.ca\/fr\/ingredients\/bio-three-enterococcus-faecium-t-110\/","title":{"rendered":"Bio\u2013Three \u00a0"},"content":{"rendered":"

Enterococcus faecium T-110<\/em>  <\/p>

Clostridium butyricum TO-A  <\/em> <\/p>

Bacillus subtilis TO-A<\/em><\/p>

Bio-Three is a proprietary ingredient from Japanese company TOA BIOPHARMA\u00ae, a leader in the development and manufacturer of fermented products. Bio-Three is composed of 3 specific probiotic strains: Enterococcus faecium<\/em> T-110, Clostridium butyricum<\/em> TO-A and Bacillus subtilis<\/em> TO-A.  While these strains are relatively new to the North American market, they have been widely used in hospitals and pharmacies throughout Asia since 1941. These bacterial species act in a symbiotic manner, such that each facilitates the proliferation of the others. Further each strain will yield unique metabolites which aid in physiological functions including metabolism, development and homeostasis of immunity. <\/p>

Clostridium butyricum <\/em>\u2013 produces large amounts of a short chain fatty acid call butyrate. There are upwards of 60 human clinical studies<\/strong> published on the safety and efficacy of Clostridium butyricum<\/em>.<\/p>

Enterococcus faecalis <\/em>lowers the pH of the gut to make is more inhospitable to pathogenic bacteria. It also produces anti-bacterial compounds called bacteriocins that can inhibit harmful bacteria.  <\/p>

Finally, Bacillus mesentericus<\/em> exponentially increases the growth of bifidobacteria which are one of the most critical and beneficial classes of bacteria in the gut. <\/p>

Technical insights:<\/strong> <\/p>