3,3`-Diindolymethane (DIM)
DIM is derived from I3C a naturally occurring compound derived from cruciferous vegetables such as broccoli, Brussels sprouts and cabbage that promotes 2-OHE. I3C needs stomach acid to then convert into 15+ compounds, of which the most predominant is DIM
DIM promotes the phase I hydroxylation of estradiol, favoring the 2-OHE pathway, and shunting metabolism away from the 16-OHE pathway in the liver. DIM helps increase the 2-OHE:16-OHE ratio while having anti-tumor actions. It also has been shown to affect the secretion of estradiol in endometriotic cells, leading to decreased pelvic pain and bleeding in women with endometriosis.
Technical insights:
- Country of origin: China
- Starting material: Indole-3-carbinol (I-3-C)
- Solvent for extraction: Ethanol
- Stored form: Powder
Non-GMO
Ingredient Benefits
Promotes healthy hormone balance
DIM can promote a healthy estrogen balance by increasing the beneficial estrogens and reducing the unwanted ones linked to estrogenic cancers.
Supports estrogen metabolism
It promotes healthy estrogen metabolism which can decrease the risk of developing estrogen related concerns.
Supports healthy cervical tissue growth
The structure of cervical tissue improved with DIM supplementation. It has also been shown to inhibit the growth of abnormal cells.
DIM has been shown to darken the colour of urine.
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