Soy isoflavones (genistein and daidzein) have been shown to mimic the effects of estrogen, making them helpful in the transition to menopause. Genistein structurally resembles estrogen and acts as a selective estrogen receptor modulator. Soy is one of the most well-known phytoestrogens, the most researched and also the most controversial.
Studies show soy isoflavones are effective in reducing the frequency and severity of hot flashes and other symptoms of menopause including mood imbalance and fatigue. For example, one study found that soy isoflavones improved mood and hot flashes in menopausal women with high body mass index (BMI) measurements. Another study found that genistein decreased all severities of hot flashes in women entering menopause within the past 12 months with higher BMI’s. A 2011 report by the North American Menopause Society states that soy-based isoflavones are “modestly effective in relieving menopausal symptoms”. This statement is significant because the report literally evaluated hundreds of studies using soy supplementation for menopause and found benefit for its use.
Technical insights:
- Country of origin: China
- Part used: Soybean (Glycine max) seed
- Solvent for extraction: Water/ethanol
- Stored form: Light yellow fine powder