5-HTP

AOR04329

Supports Positive Mood

  • A precursor to serotonin
  • Supports healthy mood balance and sleep patterns
  • Helps alleviate migraines and fibromyalgia
  • Flexible dosing options for varying needs
Gluten Free
Non-GMO
Vegan

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5-HTP is primarily used to support mood through its ability to boost serotonin levels. It has been compared to various tricyclic antidepressants, and has been found to be as effective with fewer side effects and quicker effectiveness. Since serotonin and melatonin are involved in regulating the sleep/wake cycle, 5-HTP also enhances sleep quality. Additionally, research supports a role for 5-HTP in reducing migraines and the symptoms of fibromyalgia. Studies in Spain and Italy found that 5-HTP was comparable to the drug methysergide in alleviating the symptoms of migraines (over 70% in both groups) while eliciting considerably fewer side effects. Fibromyalgia patients have been found to have low serotonin levels and have shown symptomatic improvement with the use of tricyclic and SSRI antidepressants. Several clinical trials have confirmed significant improvements in symptoms, including pain, morning stiffness, nervousness, and fatigue.

NPN

80010414

Discussion

5-HTP is 5-hydroxytryptophan, a metabolite of tryptophan, and an essential precursor of serotonin and melatonin. Research supports a role for 5-HTP in supporting mood balance and relieving the symptoms of fibromyalgia. AOR’s 5-HTP is naturally- sourced from the seeds of the griffonia shrub.

Guarantees

AOR™ guarantees that all ingredients have been declared on the label. Contains no wheat, gluten, corn, nuts, peanuts, sesame seeds, sulphites, mustard, soy, dairy, eggs, fish, shellfish or any animal byproduct.

Adult Dosage

For healthy mood balance, take 1 to 2 capsules three times daily with food; for relief of symptoms of fibromyalgia, take 2 capsules three to four times daily with food. To minimize gastrointestinal side effect risk, start at 50-100 mg two to three times daily and slowly increase to an effective dose over 2 weeks. Use for a minimum of 1 week to see beneficial effects for mood balance and 2 weeks for the alleviation of fibromyalgia symptoms. Consult a health care practitioner if symptoms persist or worsen or for use beyond one year.

Warning

Do not use if you have scleroderma, if you are pregnant, breastfeeding, or trying to conceive. Not to be used by individuals under the age of 18 or those with a medical condition. This product contains corn, do not use if you have an allergy. See Reverse for more cautions.

Main Application
  • Anxiety disorders
  • Depression
  • Fibromyalgia
  • Insomnia
  • Migraine headache
  • Obesity
Disclaimer

The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide or replace medical advice to individuals from a qualified health care professional. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

Serving Size: 1 Capsule
Amount Per Serving
% Daily Value
L-5-Hydroxytryptophan (griffonia seed extract)
50 mg

† Daily value not established

Non-medical Ingredients: microcrystalline cellulose, sodium stearyl fumarate. Capsule: hypromellose.

Background

5-Hydroxytryptophan- The Immediate Serotonin Precursor.

5-Hydroxytryptophan (5-HTP), a metabolite of tryptophan, is derived from the seed of Griffonia simplicifolia, a small shrub tree that grows off the Ivory Coast and Ghana. 5-HTP is then processed in France. 5-HTP can also be made synthetically in a laboratory. Natural 5-HTP is devoid of any “peak x” contaminants.

It is well-established that one of the basic physiological causes of depression is low serotonin levels. Low serotonin levels may also be associated with conditions other than depression, including anxiety, insomnia, aggressiveness, migraine headaches, fibromyalgia, and some obsessive-compulsive and appetite disorders.

Unfortunately, serotonin taken as a supplement cannot penetrate the blood-brain barrier (BBB). However, naturally derived 5HTP, a serotonin precursor, is well absorbed orally (70%) and penetrates the BBB, where it is converted into serotonin. Food does not interfere with its absorption.

 

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