Proven networking antioxidants
- Helps reduce inflammation and cellular damage that contributes to aging
- Superior protection over other antioxidant formulas
- A dynamic team of antioxidants which can “recycle” one another
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Antioxidants are nutrients found in all types of fruits and vegetables, plants, nuts and seeds. They help to protect the body from the damage caused by toxic molecules called free radicals. Free radicals play a role in the aging process and the development of most diseases including cataracts, heart disease, infertility, arthritis, abnormal cell development and many other chronic health conditions.
Antioxidants work by neutralizing free radicals before they can damage cells. They do this by stabilizing them but during this process, the antioxidants themselves become mild free radicals and must be “recycled” back to their original form to keep acting as antioxidant. Moreover, some antioxidants are more effective in certain locations in the body than others, meaning that you need to take the right ones for best results!
The vicious cycle of oxidation can be prevented through taking advantage of the unique complementary interactions of an elite antioxidant strike force: the Networking Antioxidants. There are five networking antioxidants: R (+)-lipoic acid, the vitamin E complex, vitamin C, coenzyme Q10, and glutathione (GSH). When taken together, these essential nutrients form a dynamic team of protectors which can “recycle” one another. By this process, networking antioxidants enhance and extend one another’s capacities.
Other antioxidants play a supporting role to the networking antioxidants. The best understood of these network-boosters are bioflavonoids and the mineral selenium. Among bioflavonoids, carnosic acid and resveratrol are particularly interesting. Carnosic acid is found in the herb rosemary while resveratrol comes from grapes. Selenium also supports the network by maintaining the body’s supply of two key enzymes.
AOR’s Antioxidant Synergy offers the most powerful combination of antioxidants to reduce inflammation and cellular damage that contribute to aging and chronic health conditions.
Antioxidant Synergy provides a research-backed combination of synergistic antioxidants for optimal health.
AOR™ guarantees that all ingredients have been declared on the label. Contains no wheat, gluten, nuts, peanuts, sesame seeds, sulphites, mustard, dairy, eggs, fish or shellfish
Take one capsule four times daily with food, or as directed by a qualified health practitioner.
Consult a health care practitioner prior to use if you are pregnant, breastfeeding, if you have diabetes, cystinuria, heart disease or cancer, or if you are taking blood pressure medication, blood thinners, nitroglycerin or antibiotics. Consult a health care practitioner for use beyond six weeks. If you experience sweating, paleness, chills, headaches, dizziness and/or confusion, discontinue use and consult a health care practitioner, as these may be symptoms of serious low blood sugar. This product contains corn and soy derived ingredients, do not use this product if you have such allergies.
The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide or replace medical advice to individuals from a qualified health care professional. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.
† Daily Value not established
*Contains 20 mg sodium per serving.
‡Tocotrienols: 14 mg alpha, 2 mg beta, 25 mg gamma, 7 mg delta
Non-medical Ingredients: rosemary extract (5 mg), silicon dioxide, sodium alginate, gum Arabic, maltodextrin, pea starch, palm oil, hydroxypropyl cellulose, sodium stearyl fumarate, acacia gum and fatty acid esters. Capsule : hypromellose.
Coenzyme Q10 (CoQ10)
CoQ10 is known as an antioxidant, but more predominantly as a coenzyme in the electron transport chain within mitochondria, for the production of cellular energy. CoQ10 is vital for cardiovascular function, helping to lower blood pressure and improving states of congestive heart failure. As well, CoQ10 has shown neuroprotective effects.
Alpha-lipoic acid is unique in that in addition to its antioxidant activity of scavenging free radicals, it can also chelate metals such as iron, copper and mercury. As part of its “networking abilities” it can regenerate other antioxidant nutrients such as vitamin E, vitamin C, and glutathione. Animal studies have shown that alpha-lipoic acid protects the mitochondria of heart cells against the effects of aging.
N-acetyl L-cysteine (NAC)
“BMAL1” is one of the proteins in our body that regulates the circadian rhythm (sleep/wake cycle). Low or deficient levels of this particular protein have been known to lead to premature aging and increased levels of reactive oxygen species (free radicals) in mice. One study administered NAC to mice who lacked the BMAL1 gene and found that life-long treatment of NAC significantly increased the average and maximal lifespan of these mice. Additionally NAC treatment led to reduced age-dependent weight loss and reduced cataract development.
Animal studies have shown that resveratrol treatment decreases levels of reactive oxygen species (free radicals), and restores the activities of antioxidant enzymes. Additionally, researchers reported that resveratrol may even protect against insulin sensitivity in skeletal muscle by improving mitochondrial activity and antioxidant balance.
Experiments using simple organisms have demonstrated resveratrol’s lifespan-increasing effects. The mechanism of this is through the stimulation of enzymes such as AMP-activated protein kinase and others that are activated classically by caloric restriction. Supplementation with resveratrol also seems to decrease the cognitive decline and Alzheimer’s-like symptoms associated with aging, as has been shown in animal studies. Preclinical studies suggest that resveratrol mimics the beneficial outcomes of caloric restriction by activating specific genes (such as SIRT1) that regulate aging. Additionally, its antioxidant effects may also protect neurons from oxidative damage. This evidence suggests that resveratrol may be useful for treating and preventing neurodegenerative diseases associated with aging such as Parkinson’s disease and Alzheimer’s disease.
In a randomized double-blind, placebo-controlled study, resveratrol was given for the treatment of mild-to-moderate Alzheimer’s-related dementia. Subjects were given 500mg daily with a 500mg dose increase every 13 weeks until a dose of 1000mg twice daily was reached for a final 13 weeks. Results showed that subjects given resveratrol had significantly stabilized declines in biomarkers of Alzheimer’s (fragments of amyloid precursor proteins) in both plasma and cerebrospinal fluid. Progressive declines of these fragments are characteristic of dementia which occurred significantly more in the placebo group.
In other animal models, resveratrol has shown promise in reversing the effects of metabolic syndrome. It has also demonstrated anti-inflammatory properties by inhibiting COX (cyclooxygenase) enzyme activity.
Tocotrienols are a form of vitamin E that are part of the antioxidant network and perform greater antioxidant activity to tocopherol vitamin E. One study supplemented subjects with 160mg of tocotrienols daily for 6 months and found that older individuals (>50 years) showed reduced DNA damage and chromosomal stability compared to the younger (<50-year-old) treatment group. The age-related DNA damage in older individuals improve significantly; therefore researchers suggest that tocotrienols may have a role in either or both prevention of DNA damage and DNA repair.
Skin protection against UV radiation
Tocotrienols can rapidly penetrate the skin, and therefore can prevent oxidative damage from UV radiation. In a study of subjects with photosensitivity, a single applications of a tocotrienol was able to protect the skin better than vitamin A products.
Internally, tocotrienols have a positive effect on the cardiovascular system by inhibiting oxidation of LDL cholesterol and down-regulating the enzyme HMG CoA reductase, which helps regulate cholesterol levels. Researchers have also documented the neuroprotective effects of tocotrienols.
In a trial of hypercholesterolemic patients, supplementing with 200-300mg of tocotrienol-rich fractions led to significant decreases in total and LDL cholesterol. When paired with medications such as lovastatin, lower doses of tocotrienols seem to provide similar benefits, compared to either treatment alone.
Vitamins C & E (tocopherol)
Vitamin C has many roles and effects in the body. In addition to its actions as an antioxidant, it is also essential for producing collagen, allowing vitamin C to be of importance in reducing the wrinkles and sagging of skin associated with aging.
Vitamin E, in tocopherol form, also acts as an antioxidant and anti-aging nutrient. Vitamin E protects against LDL cholesterol oxidation while higher intakes have been associated with reduced heart disease and cardiac deaths.
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