Arginine

AOR04054

L’acide aminé qui favorise la santé du cœur

  • Un précurseur naturel de l’oxyde nitrique qui facilite la circulation sanguine
  • Soutient et maintient la tension artérielle aux valeurs normales
  • Soutient la production d’énergie cellulaire
Sans Gluten
Sans OGM
Sans Soja
Végétalien

$41.19

En stock

L’arginine est un acide aminé pourvu d’importants bienfaits sur la santé. Elle est principalement reconnue comme facteur indispensable à la production d’oxyde nitrique, un facteur essentiel pour le relâchement des vaisseaux sanguins et favorisant la circulation sanguine. À travers ses effets d’augmentation des taux d’acide nitrique, l’arginine peut prévenir la formation de la plaque et des caillots sanguins, et réduire l’adhésivité des plaquettes. Des études cliniques ont montré que de fortes doses d’arginine étaient bénéfiques pour de nombreuses maladies cardiovasculaires, notamment les maladies vasculaires périphériques et l’angine de poitrine.

En plus de ses effets sur les vaisseaux sanguins, l’arginine est un précurseur de la créatine, un composé indispensable à la production de l’ATP qui est la principale source d’énergie l’élément le plus fondamental fournissant l’énergie utilisée par l’organisme humain. De plus, cet acide aminé polyvalent favorise naturellement la sécrétion de l’hormone de croissance (GH) par la glande pituitaire. La GH aide à réguler la composition du corps, les fluides du corps, la formation des os et des muscles, le métabolisme des sucres et des lipides, et éventuellement la fonction cardiaque.

Les personnes souffrant des maladies cardiovasculaires, du diabète ou du syndrome métabolique peuvent tirer grand profit d’une supplémentation en arginine puisqu’elle offre une multitude de bienfaits sur la circulation sanguine. Les athlètes aussi pourraient énormément en bénéficier puisque l’arginine favorise le bon fonctionnement du cœur, une bonne circulation sanguine et l’aptitude à l’effort.

Avantage AOR

AOR propose un supplément d’arginine de haute qualité pour améliorer la santé cardiovasculaire et globale.

NPN

80002697

Discussion

L’arginine est un acide aminé conditionnellement essentiel et le principal précurseur dans le corps pour la synthèse de l’oxyde nitrique (NO), une molécule qui aide les vaisseaux sanguins à s’ouvrir davantage améliorant ainsi la circulation sanguine. Depuis 1998, l’oxyde nitrique (NO) est reconnu comme étant la « molécule miracle » alors que trois Américains ont gagné le prix Nobel de la médecine pour leur découverte sur sa fonction dans la santé cardiovasculaire de l’organisme.

Certifie

AOR™ certifie: Que tous les ingrédients sont mentionnés sur l’étiquette. Ne contient ni blé, ni gluten, ni maïs, ni noix, ni graine de sésame, ni sulfite, ni moutarde, ni soja, ni produit laitier, ni œuf, ni poisson, ni mollusque, ni crustacé ou produit d’origine animale.

Posologie Adulte

Prendre trois capsules une à trois fois par jour à jeun, ou selon les recommandations d’un professionnel de la santé.

Mises en garde

Ne pas utiliser ce produit si vous avez eu un infarctus du myocarde (crise cardiaque), si vous êtes asthmatique, si vous êtes enceinte ou si vous allaitez. Consulter un professionnel de la santé avant de l’utiliser si vous prenez des médicaments pour des problèmes cardiovasculaires, des médicaments visant à augmenter votre taux de calcium ou du sildénafil.

Main Applications
  • Supports exercise capacity
  • Nitric oxide production
Avertissement

Les renseignements sur les produits contenus dans ce site web, y compris la description des produits, leurs effets potentiels et leurs avantages sont destinés à des fins d’information uniquement. Ils ne sont pas destinés à donner ou remplacer les renseignements médicaux ou l’avis d’un professionnel qualifié. Consulter votre médecin pour tout problème de santé

Portion: une capsule
L-Arginine HCl
600 mg

Ingrédients non médicinaux : stéarylfumarate de sodium.

Capsule : hypromellose.

BackgroundThe amino acid Arginine was first characterized in 1886 by the Swiss Chemist Ernst Schulze. Little research was conducted subsequently, however, since there was widespread belief that adequate amounts of arginine could be synthesized in the body, which undoubtedly delayed further research. In the 1930′s, research showed that arginine deprivation decreased the rate of growth and/or led to severe metabolic disorders and even death.In the last forty years, numerous studies have emphasized the diverse range of arginine’s physiological effects including release of growth hormone, glucagon and insulin, amino acid detoxification and for the synthesis of creatine – an important compound for generating ATP, or “cellular currency.” Arginine is a physiological precursor of nitric oxide, a potent vasodilator. In the mid 80′s the importance of nitric oxide (NO) as a ubiquitous signaling molecule was highlighted, which helped explain arginine’s diverse effects.Arginine is beneficial for improving the function of the cardiovascular system due to its nitric oxide-producing ability which reduces platelet aggregation and blood viscosity, improves blood flow and helps repair vascular injury. Arginine is considered a promising therapeutic agent for reducing the risk of restenosis and improving the outcome following heart transplantation and coronary bypass.In people with poor blood sugar control, it is also used for reversing the effects of high vascular glucose concentration. Studies also demonstrate the benefits of arginine for supporting male infertility, interstitial cystitis and liver and brain injury.ResearchCardiovascular HealthAn interesting study by Boger and colleagues compared the effects of a standard cholesterol drug called lovastatin (Mevacor) with the effects of arginine in cholesterol-fed rabbits. Lovastatin reduced cholesterol by 32%, but had only a weak effect on the formation of plaque. Interestingly, arginine had no effect on cholesterol yet completely blocked the formation of plaque.How did it do that? Arginine is reported to reduce the adhesion of monocytes to the endothelial cells in coronary patients and in smokers. Another mechanism through which arginine may be acting is that NO has potent free radical quenching properties and hence acts as an antioxidant.Numerous experimental and clinical studies have demonstrated the therapeutic potential of high dose arginine to support a broad spectrum of cardiovascular issues by reducing blood vessel damage and restoring blood vessel function, including peripheral vascular disease, angina and the metabolic syndrome.A small randomized, double blind, placebo-controlled study demonstrated that 6 grams of arginine improved exercise capacity in angina patients.Other BenefitsInterstitial cystitisA dose of 1.5g daily for 6 months in a clinical trial resulted in a significant decrease in urinary voiding discomfort and diminished abdominal and vaginal/urethral pain. Urinary frequency was significantly decreased.SpermatogenesisArginine has been used for treating male infertility by improving spermatogenesis. Since arginine is a precursor of NO, and NO is a potent vasodilator, it is conceivable that arginine would be of benefit in erectile dysfunction much like the mechanism of action of Viagra.Liver and brain injuryAnimal studies have reported benefits in acute liver and brain injuries.Market TrendsArginine is most commonly used to enhance exercise capacity, to improve nitric oxide production, in cardiovascular disorders and for erectile dysfunction.AOR AdvantageAOR offers a high quality arginine supplement to enhance cardiovascular and overall health.ReferencesBrunini TM, Mendes-Ribeiro AC, Ellory JC, Mann GE. Platelet nitric oxide synthesis in uremia and malnutrition: A role for l-arginine supplementation in vascular protection? Cardiovasc Res. 2007 Jan 15;73(2):359-67.Popovic PJ, Zeh HJ, Ochoa JB. Arginine and immunity. J Nutr. 2007 Jun;137(6 Suppl 2):1681S-1686S.Siasos G, Tousoulis D, Antoniades C, Stefanadi E, Stefanadis C. L-Arginine, the substrate for NO synthesis: an alternative treatment for premature atherosclerosis? Int J Cardiol. 2007 Apr 4;116(3):300-8.AbstractArginine and immunity.J Nutr. 2007 Jun;137(6 Suppl 2):1681S-1686S.Popovic PJ, Zeh HJ, Ochoa JB.For many years, dietary arginine supplementation, often combined with other substances, has been used as a mechanism to boost the immune system. Considerable controversy, however, exists as to the benefits and indications of dietary arginine due in part to a poor understanding of the role played by this amino acid in maintaining immune function. Emerging knowledge promises to clear this controversy and allow for arginine’s safe use. In myeloid cells, arginine is mainly metabolized either by inducible nitric oxide (NO) synthases (iNOS) or by arginase 1, enzymes that are stimulated by T helper 1 or 2 cytokines, respectively. Thus, activation of iNOS or arginase (or both) reflects the type of inflammatory response in a specific disease process. Myeloid suppressor cells (MSC) expressing arginase have been described in trauma (in both mice and humans), intra-abdominal sepsis, certain infections, and prominently, cancer. Myeloid cells expressing arginase have been shown to accumulate in patients with cancer. Arginase 1 expression is also detected in mononuclear cells after trauma or surgery. MSC efficiently deplete arginine and generate ornithine. Through arginine depletion, MSC may control NO production and regulate other arginine-dependent biological processes. Low circulating arginine has been documented in trauma and cancer, suggesting that MSC may exert a systemic effect and cause a state of arginine deficiency. Simultaneously, T lymphocytes depend on arginine for proliferation, zeta-chain peptide and T-cell receptor complex expression, and the development of memory. T-cells cocultured with MSC exhibit the molecular and functional effects associated with arginine deficiency. Not surprisingly, T-cell abnormalities, including decreased proliferation and loss of the zeta-chain, are observed in cancer and after trauma.Platelet nitric oxide synthesis in uremia and malnutrition: A role for l-arginine supplementation in vascular protection?Cardiovasc Res. 2007 Jan 15;73(2):359-67.Brunini TM, Mendes-Ribeiro AC, Ellory JC, Mann GE.L-arginine is the physiological precursor for nitric oxide (NO) synthesis, and availability and transport of l-arginine modulate the rates of NO biosynthesis in circulating blood cells and the vasculature. NO is involved in many vascular functions such as vasodilation and inhibition of platelet aggregation and adhesion. We have established that reduced plasma l-arginine and NO production and increased tumour necrosis factor-alpha (TNF-alpha), fibrinogen, and C-reactive protein levels in malnourished uremic patients are associated with increased aggregability of platelets. Our findings may explain the increased cardiovascular mortality in patients with deficient nutritional status, leading to inflammation, oxidative stress, impaired l-arginine-NO signalling, and platelet activation. The aim of this review is to evaluate whether disturbances in the l-arginine-NO signalling pathway in … are affected by malnutrition and inflammation. We have included a brief overview of membrane transporters mediating influx of l-arginine and other cationic amino acids, as these transporters are involved in the potential benefits of l-arginine supplementation and platelet function in malnourished uremic patients