Curcumin-95

AOR04004

Traditional Support For Joint Health

  • 95% curcumin from turmeric
  • Traditionally used in Ayurvedic medicine
  • Supports joint health
  • Natural antioxidant
Corn Free
Gluten Free
Non-GMO
Soy Free
Vegan

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Turmeric root, a revered East Indian spice, contains several types of curcuminoids, of which curcumin is the most potent and clinically studied. Curcumin-95 is a curcuminoid extract standardized to 95% pure curcumin. Curcumin is a powerful antioxidant and anti-inflammatory and has been traditionally used to treat joint pain and various types of chronic pain, although it has many other benefits. It can help protect cells and prevent oxidation of cholesterol and cell membranes, has antibacterial, antifungal and antiviral effects, blocks abnormal cellular growth, promotes healthy cholesterol levels and supports cardiovascular health.

Curcumin-95 is best used by those looking for a great antioxidant in its most natural form that has not been altered by modern technologies. It is effective for joint pain and arthritis and beneficial for overall maintenance of good health.  For an even more powerful anti-inflammatory, it is worth exploring Longvida Optimized Curcumin products which can be found here .

NPN

80020741

Discussion

Curcumin is used in Herbal medicine to help relieve joint inflammation and provides antioxidants for the maintenance of good health.

Guarantees

AOR™ guarantees that all ingredients have been declared on the label. Contains no wheat, gluten, corn, nuts, peanuts, sesame seeds, sulfites, mustard, soy, dairy, eggs, fish, shellfish or any animal byproduct.

AOR Advantage

AOR offers a standardized and potent curcumin extract, not a weak turmeric extract, that provides antioxidant, anti-inflammatory, cholesterol lowering, and antimicrobial benefits and promotes normal cell growth.

Adult Dosage

Take 3 capsules daily with/without food, or as directed by a qualified health care practitioner.

Cautions

Consult a health care practitioner prior to use if you are pregnant, taking antiplatelet medication or
blood thinners, have gallstones or a bile duct obstruction, have stomach ulcers or excess stomach acid, or if
symptoms persist or worsen with use.

Main Applications
  • Digestive health
  • Antioxidant
  • Joint health
  • Lipid metabolism
  • Healthy cell growth
  • Cardiovascular health
Disclaimer

The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide or replace medical advice to individuals from a qualified health care professional. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

Serving Size: 1 Capsule
Amount Per Serving
% Daily Value
Curcumin extract ‡
(Turmeric Extract 95% Curcuminoids (from Curcuma longa rhizome)
400 mg

† Daily Value not established

Non-medical Ingredients: Microcrystalline cellulose and Capsule (hypromellose, glycerin and purified water).

Pharmacological Properties of Curcuma longa

The benefits of Curcuma longa have been extensively researched, especially by Indian scientists.

1. Antioxidant Numerous studies have shown that the various constituents of Curcuma longa possess potent antioxidant properties. The ability of curcuminoids to reduce hydroxyl and peroxyl free radicals is well documented. Sharma reported curcumin to be an effective agent against lipid peroxidation.

2. Anti-inflammatory The Central Drug Research Institute in India found curcumin to be the major constituent responsible for the anti-inflammatory activity. The classical model for studying acute effects of anti-inflammatory agents is to test their inhibitory action on the development of rat paw edema – the exudative phase of inflammation – induced, for instance, by the local injection of carrageenan. Thus inflammation is thought to be in part due to the action of prostaglandin derivative from arachidonic acid metabolism. A detailed evaluation of curcumin as a potential non-steroidal anti-inflammatory agent by Srimal and Dhawan found curcumin to be highly effective after oral administration. Curcumin was effective in other models of inflammation including granuloma, pouch, cotton pellet, formalin-induced, and Freund’s adjuvant. Many mechanisms of action have been attributed to curcumin. Some researchers found curcumin to be less effective in adrenalectomized rats, suggesting a participation of corticoidal steroids, while others did not observe any effect of curcumin salts on steroid release from the adrenal cortex. Recently, another, more specific in-vitro method has been developed which allows the study of the inhibitory mechanism of potential drugs. By using rat peritoneal neutrophilis, curcumin was tested for the direct effect on the 5-lipooxygenase activities. Another study found that curcumin was able to inhibit the production of pro-inflammatory mediators in microglial cells that had been stimulated to mount an inflammatory response. Microglial cells are activated after brain injuries and produce proinflammatory mediators and neurotoxic compounds. Curcumin decreased the production of these compounds, apparently by blocking NF-kB, a protein signal in the pathway that leads to their production. The overexpression of pro-inflammatory cytokines contributes to diseases such as Alzheimer’s, cerebral ischemia and many degenerative and inflammatory conditions. The ability of curcumin to decrease inflammation presents an approach to slow the progression of these diseases.

3. Gastro-intestinal effects Curcumin increases mucin content, thereby protecting the gastric mucosa against irritants. Controversial data exist regarding an anti-ulcerogenic activity of curcumin. Some researchers found a protective effect of curcumin against histamine-induced gastric ulceration, while others reported an ulcerogenic effect of curcumin. Curcumin also possesses anti-spasmodic properties. Curcumin showed liver protective effects against carbon tetrachloride, D-Galactosamine and peroxide induced cytotoxicity. Curcumin increased bile acid production in dogs and rats.

4. Cardiovascular effects A sharp and transient hypotensive effect of curcumin was reported in dogs. Curcumin also inhibited collagen and adrenaline-induced aggregation of platelets but did not affect prostacyclin (PGI2) synthesis.

5. Lipid metabolism Rao and co-workers reported that rats fed with curcumin and cholesterol in their diet had only half to one-third of the serum and liver cholesterol levels compared to the controlled groups receiving cholesterol alone.

6. Anti-bacterial/Anti-fungal Curcumin inhibited growth of most organisms including: Staph aureus, Streptococci, Lactobacilli, Corynebacterium, Baccilus aureus, and Micrococcus pyogenes. The crude ether and chloroform extracts of Curcuma longa showed fungistatic activity against several dermatophytes as well as anti-amoebic activity against Entamoeba histolytica.

7. Anti-viral A 1993 study showed curcumin as an effective ally in the treatment against HIV. Curcumin was effective in inhibiting the replication of HIV in both acutely infected and chronically infected cells.

8. Promotes Normal Cell Growth The ability of various extracts of Curcuma longa to promote normal cellular activity  has been remarked by several researchers. Topical application of curcumin also significantly enhances normal cell activities. Curcumin was found to be a selective and non-competitive inhibitor of phosphorylase kinase.

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