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The health of the digestive system is essential to overall health, and the digestion of foods requires the help of many different enzymes. Recent research has discovered that supplementation with these enzymes can help support digestion, improve the health of the gastrointestinal system, enhance nutrient absorption, boost immunity and alleviate the gastrointestinal burden of digesting food.
Digestase 2.0 is a new and improved vegetarian enzyme formula containing a mixture of plant-based enzymes critical to digestion: amylase which digests long-chain polysaccharides, two types of protease which digest complex proteins, lipase which digests fats, and invertase which digests sucrose. New additions to Digestase 2.0 include cellulase which digests cellulose fibres, lactase which digests lactose, and alpha galactosidase which digests oligosaccharides (the complex carbohydrates found in beans and legumes) and reduces gas and bloating associated with such foods. Besides improving digestion, these enzymes can also reduce inflammation, and have been shown to speed up recovery times after injury.
Those who experience digestive discomfort or who are looking to improve gastrointestinal health can benefit from Digestase 2.0. Digestase 2.0 contains enzymes from plant sources making it suitable for vegetarians and vegans.
Digestase 2.0 is formulated with a full range of digestive enzymes that activate at different areas of the digestive tract to provide better and faster relief from digestive discomfort. Digestase 2.0 assists in the digestion of carbohydrates, fats, proteins and lactose which helps reduce symptoms of indigestion such as gas, bloating and irregularity.
|Serving Size: 1 Capsule||Amount||% Daily|
|Amylase (from Aspergillus oryzae)||3,000 DU†/75 mg|
|Protease (from A. oryzae)||20,200 HUT†/40.4 mg|
|Protease (from Aspergillus niger)||10.1 SAP†/9.4 mg|
|Alpha Galactosidase (from A. niger)||86.67 GalU†/8.7 mg|
|Invertase (from Saccharomyces cerevisiae)||400 SU†/4 mg|
|Lactase (from A. oryzae)||3,000 ALU†/30 mg|
|Lipase (from A. niger and Rhizopus oryzae)||250 LU†/12.5 mg|
|Cellulase (from A. niger)||600 CU†/8 mg|
microcrystalline cellulose, sodium stearyl fumarate. Capsule: hypromellose.
AOR™ guarantees that all ingredients have been declared on the label. Contains no wheat, gluten, peanuts, sesame seeds, sulphites, mustard, soy, dairy, eggs or any animal byproduct.
Take 1 capsule three times daily with food, or as directed by a qualified health care practitioner.
Do not use if you are pregnant or breastfeeding. Discontinue use and consult a health care practitioner if symptoms persist or worsen or for prolonged use. Consult a health care practitioner prior to use if you have gastrointestinal lesions/ulcers, diabetes, if you are having surgery, or if you are taking anticoagulants, anti-inflammatories or other enzyme products. Headaches, heartburn, bloating and hypersensitivity (e.g. allergy) have been known to occur; in which case, discontinue use.
The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide or replace medical advice to individuals from a qualified health care professional. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.
The Burden of Digestion
The digestive system is essential to health. The digestion of foods requires the help of many different enzymes. Recent research has discovered that supplementation with these enzymes can help with digestion, improve the health of the gastrointestinal system, enhance nutrient absorption and alleviate the gastrointestinal burden of digesting food.
Digestase 2.0 is a new and improved formula based on the most advanced study of the human digestive system. It contains a mixture of digestive enzymes from a variety of sources to guarantee their function at different pH ranges, and to ensure healthy digestion.
The proteins, fats, polysaccharides and other nutrients that we consume in our foods cannot be used by our bodies as such, but must first be broken down into smaller units. This process requires the help of many enzymes found in the mouth, stomach, pancreas and intestines.
The principle behind digestive enzyme formulations is simple: to improve digestion and to alleviate the gastrointestinal burden of digesting the food we eat. AOR’s latest enzyme supplement has been rigorously assessed in an experimental model designed to replicate human digestion. Digestase 2.0 is a vegetarian and comprehensive enzyme formula with the basic premise of enhancing the digestion of food. The formula contains seven different types of enzymes including two sources of proteases and lipases to broaden activity and ensure viability under a variety of pH profiles.
Enzymes for Eating
Digestase 2.0 contains a mixture of several enzymes critical to digestion. Amylase digests long-chain polysaccharides or starches, proteases digest complex proteins, lipase digests fats, and invertase digests sucrose. New additions to Digestase 2.0 include cellulase which digests cellulose fibres, lactase which digests lactose, and alpha galactosidase which digests oligosaccharides (like those found in beans and legumes) and reduces gas and bloating associated with such foods. Besides improving digestion, these enzymes can also reduce inflammation, and have been shown to speed up recovery times after injury.
Using a new technology that replicates the human stomach and small intestines, the efficacy of Digestase 2.0 as a digestive aid was assessed. Digestase 2.0 supplementation improved the following digestive processes:
Under normal digestive conditions: Digestase 2.0 more than doubled the absorption of carbohydrates and increased the absorption of protein in the ileum while protein absorption remained essentially the same in the jejunum.
Under impaired digestive conditions: differences were even greater: glucose absorption in the jejunum increasing 9-fold and protein digestion increasing significantly in both the jejunum and ileum.
The health benefits of enzyme supplementation are not limited to the absorption of nutrients. Supplemental enzymes relieve digestive organs. Animal experiments are clear: enzyme supplementation results in a healthier intestinal brush border and better nutrient accretion.
Supplemental enzymes also reduce inflammation and speed up recovery. Studies in athletes have shown improved recovery time when supplementing with enzymes. Similarly, patients undergoing surgery recover more quickly if they are prescribed enzymes. Enzymes facilitate chemical reactions, improve digestion, support digestive organs and hasten recovery. For the first time, a digestive enzyme has been tested and shown to support digestion.
Digestive enzymes are generally used by those who are interested in improving their digestive and overall health condition. Not all enzyme formulas are comprehensive and include effective amounts of enzymes to benefit digestive health. Enzymes are also increasing in popularity for the purposes of reducing inflammation and healing scar tissue.
Digestase 2.0TM is formulated based on extensive and up to date scientific research conducted by a European Research Organization called TNO, in the most advanced study on the human digestive system. This formula contains two types of proteases and lipases that are activated at different pH ranges in order to facilitate guaranteed protein digestion. In total, seven types of enzymes are included in the formula to enhance overall digestion and nutrient absorption. This formula also provides anti-inflammatory benefits. Digestase 2.0 is the world’s first digestive enzyme supported by research.
Layer P, Keller J. Lipase supplementation therapy: standards, alternatives, and perspectives. Pancreas. 2003 Jan;26(1):1-7. Review.
Lomax E. The use of oral proteolytic enzymes in the post-lipoplasty patient. Case report (unpublished)
Meng X, Slominski BA, Guenter W. The effect of fat type, carbohydrase, and lipase addition on growth performance and nutrient utilization of young broilers fed wheat-based diets. Poult Sci. 2004 Oct;83(10):1718-27.
Miller PC, Bailey SP, Barnes ME, Derr SJ, Hall EE. The effects of protease supplementation on skeletal muscle function and DOMS following downhill running. J Sports Sci. 2004 Apr;22(4):365-72.
Ritz CW, Hulet RM, Self BB, Denbow DM. Growth and intestinal morphology of male turkeys as influenced by dietary supplementation of amylase and xylanase. Poult Sci. 1995 Aug;74(8):1329-34.
Zeijdner E, Havenaar R, (2000). The Fate of orally administered compounds during passage through the gastrointestinal tract simulated in a dynamic in vitro model (TIM). European pharmaceutical Contractor, Febr. Isue: 76-81
Zeijdner E, Mohede R, I.C.M. (1999). Latest tool for screening new clinical foods. A dynamic, computer-controlled model of the human gastrointestinal tract is the most up-to-date technology for testing new foods. New World Health 199-2000: 105.a
Effects of a dietary Aspergillus oryzae extract containing alpha-amylase activity on performance and carcass characteristics of finishing beef cattle.
J Anim Sci. 2007 Mar;85(3):802-11.
Tricarico JM, Abney MD, Galyean ML, Rivera JD, Hanson KC, McLeod KR, Harmon DL.
Three experiments were conducted to examine the effects of an Aspergillus oryzae extract containing alpha-amylase activity on performance and carcass characteristics of finishing beef cattle. In Exp. 1, 120 crossbred steers were used in a randomized complete block design to evaluate the effects of roughage source (alfalfa hay vs. cottonseed hulls) and supplemental alpha-amylase at 950 dextrinizing units (DU)/kg of DM. Significant roughage source x alpha-amylase interactions (P < 0.05) were observed for performance. In steers fed cottonseed hulls, supplemental alpha-amylase increased ADG through d 28 and 112 and tended (P < 0.15) to increase ADG in all other periods. The increases in ADG were related to increased DMI and efficiency of gain during the initial 28-d period but were primarily related to increased DMI as the feeding period progressed. Supplemental alpha-amylase increased (P = 0.02) the LM area across both roughage sources. In Exp. 2, 96 crossbred heifers were used in a randomized complete block design with a 2 x 3 factorial arrangement of treatments to evaluate the effects of corn processing (dry cracked vs. high moisture) and supplemental alpha-amylase concentration (0, 580, or 1,160 DU/kg of DM). Alpha-amylase supplementation increased DMI (P = 0.05) and ADG (P = 0.03) during the initial 28 d on feed and carcass-adjusted ADG (P = 0.04) across corn processing methods. Longissimus muscle area was greatest (quadratic effect, P = 0.04), and yield grade was least (quadratic effect, P = 0.02) in heifers fed 580 DU of alpha-amylase/kg of DM across corn processing methods. In Exp. 3, 56 crossbred steers were used in a randomized complete block design to evaluate the effects of supplemental alpha-amylase (930 DU/kg of DM) on performance when DMI was restricted to yield a programmed ADG. Alpha-amylase supplementation did not affect performance when DMI was restricted. We conclude that dietary alpha-amylase supplementation of finishing beef diets may result in increased ADG through increased DMI under certain dietary conditions and that further research is warranted to explain its mode of action and interactions with dietary ingredients.
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