Helps relieve menopause symptoms
- Helps reduce hot flashes and night sweats while also promoting mood balance
- Helps balance hormones, reducing the risk of post-menopausal diseases
- Provides four of the most effective and research-backed phytoestrogen
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Fem Adapt is AOR’s premium menopause formula that is especially useful for hot flashes. While many formulas on the market contain ingredients with minimal research in menopausal women, doses that are too low or unstandardized botanical extracts, Fem Adapt provides the most powerful, clinically studied, standardized phytoestrogens in research-backed doses. Fem Adapt contains flax lignans, soy isoflavones, black cohosh and a standardized hops extract, which collectively can reduce the severity and frequency of hot flashes and other menopausal concerns.
AOR’s Fem Adapt formula not only provides safe and effective relief from menopausal symptoms, but also provides protection against health problems for which the risk increases after menopause, such as cardiovascular complications, osteoporosis and others. This is due to the mild estrogenic activity of the phytoestrogens in the product, which can serve as natural hormone replacement therapy.
Additionally, some of the ingredients in Fem Adapt have been used in herbal medicine to help relieve premenstrual symptoms, including abdominal cramps, muscle and joint pain, nerve pain like sciatica and nervous tension.
AOR’s Fem Adapt includes standardized clinically tested natural ingredients that have been demonstrated to safely and effectively alleviate some of the uncomfortable and undesirable symptoms associated with menopause. There is also some evidence to suggest that phytoestrogens, and those from soy in particular, can help alleviate the symptoms of PMS including menstrual migraines.
Fem Adapt was formulated with the most effective natural substances known to help relieve the symptoms associated with menopause. It is used in herbal medicine to help relieve premenstrual symptoms, including pain associated with menstruation.
AOR™ guarantees that all ingredients have been declared on the label. Contains no wheat, gluten, peanuts, dairy, eggs, shellfish or any animal byproduct.
Take two capsules daily, or as directed by a qualified health care professional. Take a few hours before or after taking other medications or natural health products. Consult a health care practitioner for use beyond one year.
Consult a health care practitioner prior to use if you are breastfeeding, taking blood thinners, have a history of hormonal or gynecological disease including ovarian cancer, endometriosis or uterine fibroids, have a liver disorder or develop liver-related symptomsn (e.g. abdominal pain, jaundice, dark urine), are taking hormone replacement therapy (HRT) including thyroid hormone replacement therapy or have depression or related diseases. Discontinue use and consult a health care practitioner if you experience breast pain, discomfort or tenderness or if you experience a recurrence of menstruation and/or uterine spotting. Consumption with alcohol, other medications or natural health products with sedative properties is not recommended. Some people may experience drowsiness. Exercise caution if operating heavy machinery, driving a motor vehicle or involved in activities requiring mental alertness. Hypersensitivity such as an allergy has been known to occur in rare cases, in which case discontinue use. Consult a health care practitioner if symptoms persist or worsen, or for use beyond one year. This product contains corn and soy derived ingredients, do not use if you have such allergies.
Ensure you are up-to-date on mammograms and gynecological evaluations prior to use. Do not use if you are pregnant, if you currently have or previously had breast cancer or breast tumours, have a predisposition to breast cancer as indicated by an abnormal mammogram, biopsy or have a family member with breast cancer.
- Women’s health
The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide or replace medical advice to individuals from a qualified health care professional. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.
*AIE: Aglycone Isoflavone Equivalents
†LIFENOL® is a registered trademark of Naturex, Inc.
Non-medicinal Ingredients: Microcrystalline cellulose, silicon dioxide, maltodextrin and tricalcium phosphate.
Genistein and Estrogen
Genistein has been shown in laboratories to have estrogenic effects by weakly binding to estrogen receptors (ER). For this reason it is commonly referred to as a phytoestrogen. It binds more strongly to ER-β than ER-α, which then competes with estradiol for binding to these estrogen receptors. The β -estrogen receptor predominates in the heart, vasculature, bone, and bladder and may account for some of genistein’s beneficial effects. Genistein binds weaker to ERs than estradiol, and induces estrogenic effects with less potency than estradiol. This suggests that genistein selectively binds to estrogen receptors, serving as a natural alternative to conventional hormonal therapy, which has been associated with an increased risk of breast cancer, stroke, venous thromboembolism and coronary heart disease.
Genistein and Osteoporosis
Genistein structurally resembles estrogen and acts as a selective estrogen receptor modulator. Genistein may help control bone cell metabolism by its higher affinity for β-estrogen receptors, which are found more in bone than α-estrogen receptors, which are found more in reproductive tissue. Genistein has been shown to directly inhibit osteoclast activity, which is involved in the destruction of bone and increase osteoblastic proliferation, which is involved in bone formation. Studies have shown genistein to decrease bone resorption markers and increase bone formation markers, leading to a net gain in bone mass. These findings have been confirmed using the urinary excretion markers pyridinoline and deoxypyridinoline (markers of bone resorption), which were found to be decreased in research subjects taking genistein. In one clinical trial lasting over two years in duration, subjects supplemented with genistein and experienced an improvement in bone mineral density (BMD), as well as a significant decrease in bone fracture risk.
SDG or secoisolariciresinol diglucoside from flax (Linum usitatissimum) is specialized lignan that has high bioavailability due to the monomers compared to the large polymers usually found in traditional flax supplements. SDG is converted by mammalian bacteria in the colon into enterodiol (END) and enterolactone (ENL) which are the active human lignans. These lignans (remarkably similar to the human estrogens) are extensively studied for their cardioprotective, menopausal, bone density and inflammatory effects in humans. A recent study in women using 500mg of SDG for 6 weeks was found to reduce ultra-sensitive C-reactive protein, one of the inflammatory markers. Another study showed that women had significantly reduced cholesterol and other heart health indices when taking SDG monomers. Animal studies have confirmed the benefits of SDG for tissues in the breast, colon, ovary and the endometrium. An important finding was that SDG exerts a potent anti-angiogenesis effect particularly by inhibiting the vascular endothelial growth factor (VEGF) and promoting apoptosis. It is also hypothesized that lignans stimulate sex hormone binding globulin (SHBG) from the liver, inhibiting aromatase activity.
A double blind randomized cross over study (specifically designed to take into account the high degree of “placebo” effect common with menopausal studies) showed that 8PN reduced hot flashes and night sweats and may be a good adjunct to other post-menopausal treatments.
The effects of black cohosh on menopausal symptoms such as hot flashes and night sweats are under scrutiny, as are its traditional uses for pain related to PMS and its content of estrogen-like compounds. However, more recent research has revealed that black cohosh may have serotonin-like compounds that activate serotonin receptors. This is important because low mood can be secondary symptoms to menopause and PMS. In addition, newer clinical studies have shown that compounds in black cohosh may inhibit the formation of osteoclasts which are cells that break down bone. Bone loss is one of the top concerns among post-menopausal women. For these reasons, black cohosh is still considered to be advantageous for menopausal women.
Several older studies also found some of these ingredients helpful for reducing migraines associated with menstruation. One study found that a blend of the phytoestrogens black cohosh, dong quai and soy isoflavones significantly reduce the frequency of migraine attacks versus placebo from months two to six. Another study administered genistein and daidzein, two phytoestrogens found in soy isoflavones and found reduced frequency of migraine attacks over three months.
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