Pro Tri B12


Combines three different forms of vitamin B12

  • Combines three different forms of vitamin B12: hydroxycobalamin, adenosylcobalamin and methylcobalamin
  • High dose of bioavailable and active forms of B12
  • Clean sourcing from Europe
Gluten Free

Pro Tri B12 is a combination of three independent and active forms of vitamin B12. Methylcobalamin, hydroxocobalamin and adenosylcobalamin are three distinct cobalamin factors, each with their own unique benefits. When taken together, they provide an appropriate dose of bioavailable and active forms of B12 for comprehensive support in replenishing a deficiency.

AOR Advantage

Unlike many other sources of vitamin B12 on the market, AOR presents vitamin B12 in its three most active and bioavailable forms. The combination of its two cofactor forms may make supplementation more efficient and can restore B12 levels faster than with one form alone. Additionally, AOR’s ingredients are sourced in Europe and are environmentally certified. Pro Tri B12 is free of harmful additives.




Methylcobalamin, Hydroxocobalamin and Adenosylcobalamin are active sources of vitamin B12, each form with its own unique benefits. When combined, they quickly help replenish any Vitamin B12 deficiency in the body and assist it in metabolizing carbohydrates, fats and proteins. They also help in the formation of red blood cells.


AOR™ guarantees that all ingredients have been declared on the label. Contains no wheat, gluten, nuts, peanuts, sesame seeds, sulphites, mustard, soy, dairy, eggs, fish, shellfish or any animal by-product.

Adult Dosage

Dissolve one lozenge under the tongue first thing in the morning, or as directed by a qualified health care practitioner.


Consult a health care practitioner for use beyond four months. If you are pregnant or breastfeeding, consult a health care practitioner prior to use. This product contains corn derived ingredients, do not use if you have a corn allergy.


The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide or replace medical advice to individuals from a qualified health care professional. Consult with a health care practitioner if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

Main Applications

• Vitamin B12 deficiency
• Malabsorption issues
• High-risk groups

Serving Size: One Lozenge
Vitamin B12
5 mg
3.5 mg
1 mg
500 mcg

Non-medicinal Ingredients: Hydroxypropyl cellulose, ascorbyl palmitate, rice syrup, xylitol, microcrystalline cellulose and distilled water.

Vitamin B12 is used as a cofactor in many enzymatic processes. Each form of cobalamin – methyl, hydroxy, adenosyl – is vital to different cellular processes. A deficiency in B12 may cause a variety of symptoms over time, including fatigue, poor balance, cognitive changes, depression, and increased cardiovascular risks.

Deficiency can be caused by poor diet, impaired microbiota, malabsorption disorders, or the use of certain medications. Populations at risk include the elderly and vegans. Chronic antibiotic use and genetic factors can also play a role.

Roles of B12 Cofactors in the Body

Cobalamin is only active as a cofactor in two forms: adenosylcobalamin and methylcobalamin. Hydroxocobalamin and the less desirable cyanocobalamin are considered precursors that can be converted into these cofactor forms under the right conditions.

Methylcobalamin is involved in the critical metabolic process of methylation, allowing for homocysteine recycling, as well as the production of red blood cells, neurotransmitters and DNA.

Adenosylcobalamin is active within mitochondria to support carbohydrate and fat metabolism, and energy production. Among the enzymes it activates, methylmalonyl-CoA mutase (MMCoA mutase) is one of the most important. When activity is blocked, increased levels of methylmalonic acid (MMA) can lead to demyelination of neurons.

Hydroxocobalamin acts as a precursor to both the above forms and has independent detoxifying actions. It is also bound to the body’s own transport molecules and serves as storage for later conversion, ensuring a longer-lasting supply.

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