Cardiovascular

Review on pharmacognostic, phytochemical and pharmacological characteristics of medicinal plants which can be used to design a novel ayurvedic formulation to treat hypertension in multidimensional approaches

This review from 2023 evaluates extraction methods of the active phytoconstituents and pharmacognostic, physiochemical, phytochemical and quantitative analysis parameters, and the different pharmacological modes of action for ayurvedic plants traditionally used for the management of blood pressure. Concluding that Boerhavia diffusa consists of active ingredients: Liriodendron & Syringaresinol mono β-D-Glucosidase which can exhibit Ca2+ channel …

Review on pharmacognostic, phytochemical and pharmacological characteristics of medicinal plants which can be used to design a novel ayurvedic formulation to treat hypertension in multidimensional approaches Read More »

Ethnomedicinal uses, phytochemistry and pharmacological properties of the genus Boerhavia

This review from 2016 focused on traditional uses, phytochemistry, pharmacology and toxicology of Boerhavia genus to support potential scope for advanced ethnopharmacological study. 180 compounds from Boerhavia genus were isolated, of which B. diffusa alone, shared around 131 compounds and for most of which it is currently an exclusive source. References: Patil, K. S., & …

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Calcium supplementation in clinical practice: A review of forms, doses and indications

This review from 2007 is the only comprehensive assessment of the various types of calcium salt forms. Suggesting that calcium carbonate offers an effective and cost-efficient form that should be taken with a meal to ensure optimal absorption. References: Straub DA. Calcium supplementation in clinical practice: a review of forms, doses, and indications. Nutr Clin …

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Role of vitamin C in the function of the vascular endothelium

This review from 2013 covers the use of vitamin c in various salt forms and its impact on vascular health. These functions include increasing the synthesis and deposition of type IV collagen in the basement membrane, stimulating endothelial proliferation, inhibiting apoptosis, scavenging radical species and sparing endothelial cell-derived nitric oxide to help modulate blood flow. …

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Final report of the safety assessment of L-ascorbic acid, calcium ascorbate, magnesium ascorbate, magnesium ascorbyl phosphate, sodium ascorbate, and sodium ascorbyl phosphate as used in cosmetics

In 2005 researchers reviewed evidence on the safety and tolerability of ingested and topical use of commercially available ascorbic acid preparations. Given the widespread use in cosmetics, authors assessed preclinical evidence relating to L-ascorbic acid, calcium ascorbate, magnesium ascorbate, magnesium ascorbyl phosphate, sodium ascorbate and sodium ascorbyl phosphate. Helps guide industrial selection of ascorbic acid …

Final report of the safety assessment of L-ascorbic acid, calcium ascorbate, magnesium ascorbate, magnesium ascorbyl phosphate, sodium ascorbate, and sodium ascorbyl phosphate as used in cosmetics Read More »

Calcium supplementation in clinical practice: A review of forms, doses and indications

This review from 2007 is the only comprehensive assessment of the various types of calcium salt forms. Suggesting that calcium citrate can be taken without food and is the supplement of choice for individuals with achlorhydria or who are taking histamine-2 blockers or protein-pump inhibitors. References: Straub DA. Calcium supplementation in clinical practice: a review of …

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Choline supplements: An update

From 2023, this review of supplemental forms of choline currently available includes choline alfoscerate also known as alpha-glycerophosphocholine (α-GPC or GPC), choline bitartrate, lecithin and citicoline. One of the most used is choline bitartrate, which has shown favorable effects both in preclinical and clinical studies, especially in terms of improved cognitive function. References: Kansakar U, …

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The effect of natural antioxidants in the development of metabolic syndrome: Focus on bergamot polyphenolic fraction

In this comprehensive review from 2020, authors examined evidence supporting the use of bergamot polyphenolic fractions in prevention of metabolic syndrome. Including research on the lipid lowering and anti-diabetic effects of the polyphenols in bergamot. References: Carresi, C., Gliozzi, M., Musolino, V., Scicchitano, M., Scarano, F., Bosco, F., Nucera, S., Maiuolo, J., Macrì, R., Ruga, …

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Hypoglycemic and hypolipemic effects of a new lecithin formulation of bergamot polyphenolic fraction: A double blind, randomized, placebo-controlled study

In a randomized, placebo-controlled study, 237 patients suffering from a combination of hypercholesterolemia, hyperlipidemia and hyperglycemia received 0, 500 or 1,000 mg/day of bergamot extract (23–27% flavonoids by weight) for 30 days. Patients receiving bergamot extract exhibited reductions in LDL-C of 23–27% (at 500 mg/day) and 33–39% (at 1,000 mg/day). Similar reductions were observed in …

Hypoglycemic and hypolipemic effects of a new lecithin formulation of bergamot polyphenolic fraction: A double blind, randomized, placebo-controlled study Read More »

Effect of bergamot on lipid profile in humans: A systematic review

This systematic review published in 2020 reviewed 12 articles related to the lipid modifying properties of bergamot extracts. Authors reported most studies demonstrated a significant decrease in total cholesterol (12.3% to 31.3%,), triglycerides (11.5% to 39.5%) and LDLc (7.6% to 40.8%). Eight trials reported HDLc increase after intervention with bergamot. References: Lamiquiz-Moneo, I., Giné-González, …

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