Colitis

A double blind, randomized, placebo-controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee. 

In this 2008, double-blind, randomized, placebo-controlled study on 75 osteoarthritis (OA) patients, the researchers evaluated the efficacy and safety of 5-Loxin in the treatment of OA of the knee over a 90-day period. 5-Loxin is a novel Boswellia serrata extract enriched with 30% 3-O-acetyl-11-keto-beta-boswellic acid (AKBA), which exhibits potential anti-inflammatory properties by inhibiting the 5-lipoxygenase …

A double blind, randomized, placebo-controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee.  Read More »

Boswellia serrata preserves intestinal epithelial barrier from oxidative and inflammatory damage 

This 2015 preclinical paper examines the pharmacological mechanisms mediated by BSE, in protecting intestinal epithelial barrier from inflammatory damage and supports its use as a safe adjuvant in patients affected by IBD. Fortification of the intestinal barrier function is still a challenge in acute or chronic colonic cell lines and supplementation with Boswellia demonstrated key …

Boswellia serrata preserves intestinal epithelial barrier from oxidative and inflammatory damage  Read More »

Bovine colostrum applications in sick and healthy people: A systematic review 

This comprehensive review published in 2021 evaluated evidence relating to the clinical use of exogenous supplemental bovine colostrum in human health. 24 full text studies were selected and reviewed regarding intestinal and respiratory recovery. The mechanism of action seemed to suggest bovine colostrum modulates the immune response and may increase sIgA.   References: Guberti, M., Botti, …

Bovine colostrum applications in sick and healthy people: A systematic review  Read More »

Bovine colostrum: Its constituents and uses 

This comprehensive review published in 2021 in Nutrients, reviews the main constituents, quality control and an overview of the use of bovine colostrum in health and disease.   Bovine colostrum active constituents include immunoglobulins, cytokines, oligosaccharides and immune factors. It also contains growth factors and hormones which account for many of the health benefits. Multiple studies …

Bovine colostrum: Its constituents and uses  Read More »

The use of bovine colostrum in medical practice and human health: Current evidence and areas requiring further examination 

The prestigious scientific journal Nutrients published this special edition in 2022 for a comprehensive review of the health potential of bovine colostrum supplementation.   Including five review articles, use in gastrointestinal health and disease, sports nutrition, pediatrics, and immune support. It also includes a systematic review of its clinical use and an original research article examining …

The use of bovine colostrum in medical practice and human health: Current evidence and areas requiring further examination  Read More »

Clinical effectiveness of probiotics therapy (BIO-THREE) in patients with ulcerative colitis refractory to conventional therapy.  

A single-arm pilot study was designed to evaluate the effect of Probiotic-3 against symptoms associated with treatment-refractory ulcerative colitis. Twenty patients with mild to moderate colitis took three Probiotic-3 capsules, three times a day, for four weeks. The primary outcome measure was resolution of symptoms. In total, 45% of patients exhibited complete remission, with 10% …

Clinical effectiveness of probiotics therapy (BIO-THREE) in patients with ulcerative colitis refractory to conventional therapy.   Read More »

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