Foundational

Does Branched-Chain Amino Acids (BCAAs) Supplementation Attenuate Muscle Damage Markers and Soreness after Resistance Exercise in Trained Males? A Meta-Analysis of Randomized Controlled Trials

This meta-analysis published in 2021 relating to the effect of BCAAs supplementation on plasma muscle damage markers and soreness after resistance exercise in only trained males. Nine studies met the inclusion criteria with a total of 278 participants ranging from 21.5 to 24.7 years old. Study length ranged from 1-28 days and supplementation schedules included …

Does Branched-Chain Amino Acids (BCAAs) Supplementation Attenuate Muscle Damage Markers and Soreness after Resistance Exercise in Trained Males? A Meta-Analysis of Randomized Controlled Trials Read More »

Effect of BCAA intake during endurance exercises on fatigue substances, muscle damage substances and energy metabolism substances

To determine the effects of BCAA supplementation on fatigue, muscle damage and energy metabolism after endurance exercise, this randomized, double-blind, placebo-controlled clinical trial from 2013 was carried out. These results suggest that BCAA may reduce muscle damage associated with endurance exercise.

Calcium citrate versus calcium carbonate in the management of chronic hypoparathyroidism: A randomized, double-blind, crossover clinical trial

This randomized double-blind placebo-controlled trial published in 2022 assessed the efficacy of two types of calcium forms: carbonate and citrate in the ability to increase calcium levels in individuals with parathyroid deficiencies. Both forms were effective in increasing serum calcium levels. Calcium citrate seems to have increased urine oxalate excretion which may reduce risks for …

Calcium citrate versus calcium carbonate in the management of chronic hypoparathyroidism: A randomized, double-blind, crossover clinical trial Read More »

Calcium supplementation in clinical practice: A review of forms, doses and indications

This review from 2007 is the only comprehensive assessment of the various types of calcium salt forms. Suggesting that calcium carbonate offers an effective and cost-efficient form that should be taken with a meal to ensure optimal absorption. References: Straub DA. Calcium supplementation in clinical practice: a review of forms, doses, and indications. Nutr Clin …

Calcium supplementation in clinical practice: A review of forms, doses and indications Read More »

Role of vitamin C in the function of the vascular endothelium

This review from 2013 covers the use of vitamin c in various salt forms and its impact on vascular health. These functions include increasing the synthesis and deposition of type IV collagen in the basement membrane, stimulating endothelial proliferation, inhibiting apoptosis, scavenging radical species and sparing endothelial cell-derived nitric oxide to help modulate blood flow. …

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Final report of the safety assessment of L-ascorbic acid, calcium ascorbate, magnesium ascorbate, magnesium ascorbyl phosphate, sodium ascorbate, and sodium ascorbyl phosphate as used in cosmetics

In 2005 researchers reviewed evidence on the safety and tolerability of ingested and topical use of commercially available ascorbic acid preparations. Given the widespread use in cosmetics, authors assessed preclinical evidence relating to L-ascorbic acid, calcium ascorbate, magnesium ascorbate, magnesium ascorbyl phosphate, sodium ascorbate and sodium ascorbyl phosphate. Helps guide industrial selection of ascorbic acid …

Final report of the safety assessment of L-ascorbic acid, calcium ascorbate, magnesium ascorbate, magnesium ascorbyl phosphate, sodium ascorbate, and sodium ascorbyl phosphate as used in cosmetics Read More »

Calcium supplementation in clinical practice: A review of forms, doses and indications

This review from 2007 is the only comprehensive assessment of the various types of calcium salt forms. Suggesting that calcium citrate can be taken without food and is the supplement of choice for individuals with achlorhydria or who are taking histamine-2 blockers or protein-pump inhibitors. References: Straub DA. Calcium supplementation in clinical practice: a review of …

Calcium supplementation in clinical practice: A review of forms, doses and indications Read More »

Calcium citrate versus calcium carbonate in the management of chronic hypoparathyroidism: A randomized, double-blind, crossover clinical trial

This randomized double-blind placebo-controlled trial published in 2022 assessed the efficacy of two types of calcium forms: carbonate and citrate in the ability to increase calcium levels in individuals with parathyroid deficiencies. Both forms were effective in increasing serum calcium levels. References: Naciu AM, Tabacco G, Bilezikian JP, Santonati A, Bosco D, Incognito GG, …

Calcium citrate versus calcium carbonate in the management of chronic hypoparathyroidism: A randomized, double-blind, crossover clinical trial Read More »

Antioxidant capacity of different fractions of vegetables and correlation with the contents of ascorbic acid, phenolics and flavonoids

This 2011 study examined the antioxidant capacity of fractions of vegetables and pointed to an interesting observation, namely, that in vegetables with a number of flavonoids, the ascorbic acid had over ten times the bioavailability of synthetic vitamin C. Careful analysis revealed that the tannins and flavonoids such as quercetin were also considerably enhanced by …

Antioxidant capacity of different fractions of vegetables and correlation with the contents of ascorbic acid, phenolics and flavonoids Read More »

Hesperidin: A therapeutic agent for obesity

In this 2019 review study the opportunity for hesperidin rich diets in benefiting obesity was assessed. The reviewers found evidence supporting hesperidin regulation of lipid and glucose metabolism (through AMPK and PPAR mediation), direct regulation of antioxidant index and anti-apoptosis, indirect mediation inflammation (via NF-κB) for the management of obesity. References: Xiong H, Wang J, …

Hesperidin: A therapeutic agent for obesity Read More »

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