Kidney & Urinary

10 Year Outcome of Enzyme Replacement Therapy with Agalsidase Beta in Patients with Fabry Disease.

The aim of this study was to assess the clinical effect of α-galactosidase. Following supplementation, participants were assessed for severe clinical events, renal function and cardiac structure. This 10-year study documents the effectiveness of agalsidase beta (1 mg/kg/2 weeks) in patients with Fabry disease. Most patients remained alive and event-free. Patients who initiated treatment at a younger …

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Microbial Production and Biotechnological Applications of α-Galactosidase

This review published in 2020 explores the growth and purification strategies to ensure that this important enzyme is able to reach full commercial potential. References: Bhatia, S., Singh, A., Batra, N., & Singh, J. (2020). Microbial production and biotechnological applications of α-galactosidase. International journal of biological macromolecules, 150, 1294–1313. https://doi.org/10.1016/j.ijbiomac.2019.10.140

Effect of Phyllanthus niruri on metabolic parameters of patients with kidney stone: A perspective for disease prevention

In a clinical study, 56 patients with one or more kidney stones smaller than 10 mm were given an infusion (tea) of P. niruri dry extract for 12 weeks. Patients were to drink the tea daily for one week, then take a break for one week, then continue alternating treatment weeks. Patients were followed up …

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Efficacy of Phyllanthus niruri on improving liver functions in patients with alcoholic hepatitis: A double-blind randomized controlled trial

From 2021, this block randomized, double-blind, parallel-arm placebo-controlled trial was designed to assess the efficacy of P. niruri on the liver and renal function parameters, total oxidant and antioxidant levels in alcoholic hepatitis patients in comparison to placebo over a 4-week period. 71 patients were allocated into treatment and placebo arms. A 4-week administration of …

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Morus alba L. for blood sugar management: A systematic review and meta-analysis

This review from 2022 evaluates evidence relating to the effect of Morus alba on blood sugar management. Authors found 13 RCTs in 10 articles were eligible for inclusion. Long-term studies made participants take Morus alba (MA) two or three times a day, and the dosage varied from 10.8 mg to 54 mg. Results showed that Morus alba …

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