Performance

Does Branched-Chain Amino Acids (BCAAs) Supplementation Attenuate Muscle Damage Markers and Soreness after Resistance Exercise in Trained Males? A Meta-Analysis of Randomized Controlled Trials

This meta-analysis published in 2021 relating to the effect of BCAAs supplementation on plasma muscle damage markers and soreness after resistance exercise in only trained males. Nine studies met the inclusion criteria with a total of 278 participants ranging from 21.5 to 24.7 years old. Study length ranged from 1-28 days and supplementation schedules included …

Does Branched-Chain Amino Acids (BCAAs) Supplementation Attenuate Muscle Damage Markers and Soreness after Resistance Exercise in Trained Males? A Meta-Analysis of Randomized Controlled Trials Read More »

Effect of BCAA intake during endurance exercises on fatigue substances, muscle damage substances and energy metabolism substances

To determine the effects of BCAA supplementation on fatigue, muscle damage and energy metabolism after endurance exercise, this randomized, double-blind, placebo-controlled clinical trial from 2013 was carried out. These results suggest that BCAA may reduce muscle damage associated with endurance exercise.

Medicinal properties of Terminalia arjuna (Roxb.) Wight & Arn.: A review.

A double-blind, placebo-controlled study by Kapoor et al., in 2016 found 100 patients with coronary artery disease given 500 mg arjuna twice daily in addition to conventional therapy had significant decreases in hyperlipidemia and in multiple inflammatory cytokines including IL-6 and TNF-alpha. References; Amalraj A, Gopi S. (2016). Medicinal properties of Terminalia arjuna (Roxb.) Wight …

Medicinal properties of Terminalia arjuna (Roxb.) Wight & Arn.: A review. Read More »

Efficacy of Terminalia arjuna in chronic stable angina: A double-blind, placebo-controlled, crossover study comparing Terminalia arjuna with isosorbide mononitrate

In this 2002 double-blind, placebo-controlled crossover study, 58 males with chronic stable angina were recruited. Arjuna treatment was associated with significantly decreased angina frequency and the need for isosorbide dinitrate use. References: Bharani A, Ganguli A, Mathur LK, et al. (2002). Efficacy of Terminalia arjuna in chronic stable angina: a double-blind, placebo-controlled, crossover study comparing …

Efficacy of Terminalia arjuna in chronic stable angina: A double-blind, placebo-controlled, crossover study comparing Terminalia arjuna with isosorbide mononitrate Read More »

Short-term adjuvant therapy with Terminalia arjuna attenuates ongoing inflammation and immune balance in patients with stable coronary artery disease: In vitro and in vivo evidence.

In a 2015 placebo-controlled trial, 116 patients with stable coronary artery disease were given either 500 mg T. arjuna twice daily, or a placebo. After three months of treatment, arjuna therapy significantly down-regulated triglycerides, very-low-density lipoprotein (VLDL) cholesterol and other inflammatory markers compared to placebo. References: Kapoor D, Trikha D, Vijayvergiya R, et al. (2015). …

Short-term adjuvant therapy with Terminalia arjuna attenuates ongoing inflammation and immune balance in patients with stable coronary artery disease: In vitro and in vivo evidence. Read More »

A randomized, double blind placebo controlled study of efficacy and tolerability of Withania somnifera extracts in knee joint pain.

This study from 2016 is a randomized double-blind placebo-controlled trial, testing the dose-dependent effects of W. somnifera in patients with knee joint pain and discomfort. At the end of 12 weeks the high dose (i.e., 250 mg BID) group showed improvements earlier at 4 weeks and had a more significant reduction in the VAS scores …

A randomized, double blind placebo controlled study of efficacy and tolerability of Withania somnifera extracts in knee joint pain. Read More »

Role of Withania somnifera (Ashwagandha) in the management of male infertility

From 2018 this comprehensive review assessed the available evidence supporting use of Withania somnifera extracts on the management of male fertility concerns. Specifically relating to semen quality, sperm count, motility and androgens. Authors concluded that preclinical evidence supports the reduction in oxidative stress related to male infertility and may offer a promising therapeutic option. References: …

Role of Withania somnifera (Ashwagandha) in the management of male infertility Read More »

Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review.

In this 2018 systematic review 10 articles (preclinical) were included in the final analysis. These studies demonstrated that vitamin C increases type 1 collagen fibres, scar tissue formation and accelerates bone healing after fracture. References: DePhillipo, N. N., Aman, Z. S., Kennedy, M. I., Begley, J. P., Moatshe, G., & LaPrade, R. F. (2018). Efficacy …

Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review. Read More »

Clinical Applications of Astaxanthin in the Treatment of Ocular Diseases: Emerging Insights

This review, published in 2020, reviewed all the published evidence – preclinical and clinical – for the use of astaxanthin for ocular health. Preclinical evidence supports the use of astaxanthin in the prevention and treatment of glaucoma, cataracts, keratopathy and dry eyes. References:  Giannaccare, G., Pellegrini, M., Senni, C., Bernabei, F., Scorcia, V., & Cicero, …

Clinical Applications of Astaxanthin in the Treatment of Ocular Diseases: Emerging Insights Read More »

The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in humans

The aim of this study was to examine the effects of Eleutherococcus senticosus (ES) supplementation on endurance capacity, cardiovascular functions and metabolism of recreationally trained males for eight weeks. This is the first well-conducted study that shows that eight week ES supplementation enhances endurance capacity, elevates cardiovascular functions and alters the metabolism for sparing glycogen …

The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in humans Read More »

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