In 2020 authors compiled clinical and preclinical evidence relating to the use of grape seed extracts in the prevention and management of obesity. It is considered as one of the most effective plant antioxidants, and one of the most effective free radical scavengers. Authors found that GSPE has many activities, such as lowering blood lipids, improving the intestinal flora, regulating the metabolism – that contribute to the prevention of obesity.
Liu, M., Yun, P., Hu, Y., Yang, J., Khadka, R. B., & Peng, X. (2020). Effects of Grape Seed Proanthocyanidin Extract on Obesity. Obesity facts, 13(2), 279–291. https://doi.org/10.1159/000502235