This 2022 review provides an up-to-date evaluation of the current understanding of the cardioprotective mechanisms of vitamin B6. Marginal vitamin B6 deficiency appears to relate to an increased risk of inflammation-related diseases, such as cardiovascular diseases and cancers. Of all the cardiovascular diseases, heart failure is a complex clinical syndrome associated with a high mortality rate.
Kumrungsee, T., Peipei Zhang, Yanaka, N., Suda, T., & Kato, N. (2022). Emerging cardioprotective mechanisms of vitamin B6: a narrative review. European journal of nutrition, 61(2), 605–613. https://doi.org/10.1007/s00394-021-02665-2