This 2019 pilot study, examined the effects of Longvida® Optimized Curcumin in patients with knee osteoarthritis. The study group (n=17) received the optimized curcumin 80 mg or curcumin from 400 mg capsules twice daily following meals for 90 days. The control group (n=25) received Ibuprofen (400 mg) once in the morning followed by placebo (dextrin) in the evening. Both groups showed a significant and comparable improvement in VAS and WOMAC scores in alleviating pain with Ibuprofen or optimized curcumin.
Gupte PA, Giramkar SA, Harke SM, Kulkarni SK, Deshmukh AP, Hingorani LL, Mahajan MP, Bhalerao SS. Evaluation of the efficacy and safety of Capsule Longvida® Optimized Curcumin (solid lipid curcumin particles) in knee osteoarthritis: a pilot clinical study. J Inflamm Res. 2019 Jun 5;12:145-152. doi: 10.2147/JIR.S205390. PMID: 31239749; PMCID: PMC6559772.