Metabolic effects of a-lipoic acid supplementation in pre-diabetics: A randomized, placebo-controlled pilot study
In a randomized, placebo-controlled crossover pilot study, 12 pre-diabetic patients with dyslipidemia were given 600 mg of alpha-lipoic acid or a placebo daily for 30 days. Treatment with lipoic acid resulted in a significant decrease in fasting insulin levels and a decrease in HOMA-IR compared to the placebo.
References
Gosselin LE, Chrapowitzky L, Rideout TC. (2019). Metabolic effects of a-lipoic acid supplementation in pre-diabetics: a randomized, placebo-controlled pilot study. Food Funct. 10(9): 5732-8
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