In a randomized controlled trial from 2014, patients diagnosed with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) were given 1000 mg flower pollen extract daily or 600 mg ibuprofen three times daily for four weeks. At the end of the treatment period, 75% of patients in the flower pollen extract group had improvements in quality of life compared to 41% in the ibuprofen group. There were also less adverse effects in the pollen treatment group compared to the ibuprofen group.
Cai T, Wagenlehner FM, Luciani LG, Tiscione D, Malossini G, Verze P, Mirone V, Bartoletti R. Pollen extract in association with vitamins provides early pain relief in patients affected by chronic prostatitis/chronic pelvic pain syndrome. Exp Ther Med. 2014 Oct;8(4):1032-1038. doi: 10.3892/etm.2014.1861. Epub 2014 Jul 24. PMID: 25187793; PMCID: PMC4151652.