In this 2023 comprehensive review CGM and its technology as a food-grade formulation to deliver ‘free’ unconjugated curcuminoids with enhanced bioavailability and improved pharmacokinetic properties. Twenty-six manuscripts are reviewed here, including 14 pre-clinical and 12 clinical studies that have investigated CGM pharmacokinetics, safety and efficacy in various animal models and human conditions.
References:
Matthewman C, Krishnakumar IM, Swick AG. Review: bioavailability and efficacy of ‘free’ curcuminoids from curcumagalactomannoside (CGM) curcumin formulation. Nutr Res Rev. 2023 Jan 19:1-18. doi: 10.1017/S0954422423000033. Epub ahead of print. PMID: 36655498.