Published in 2023 this review aimed to provide complete evidence about the efficacy of citicoline for MCI, especially of vascular origin, but also due to other neurodegenerative disorders. With authors concluding: “citicoline has shown a consistent improvement in cognitive function in patients with MCI, especially of vascular origin. Moreover, it provides beneficial effects on vascular, Alzheimer, and mixed dementias, stroke sequelae, intracerebral hemorrhages, traumatic brain injuries, and neurodegenerative diseases. Long-term treatment with citicoline has also been demonstrated to be well-tolerated and has not been associated with severe adverse events.”
References:
Bermejo, P. E., Dorado, R., & Zea-Sevilla, M. A. (2023). Role of Citicoline in Patients With Mild Cognitive Impairment. Neuroscience insights, 18, 26331055231152496. https://doi.org/10.1177/26331055231152496