Vitamin K2, Menaquinone
Trans- Menaquinone-7, MK7
Vitamin K is an essential vitamin needed for cardiovascular, bone and liver health. Vitamin K2 is more effective than vitamin K1, the form found in plants, for these specific health effects. AOR uses a double micro-encapsulated form to protect from degradation in the capsule.
MK-7 has a half-life of about 72 hours whereas it is only about 1.5 hours for MK-4. These differences arise from the differences in the distribution and breakdown of the two MK forms. MK-4 is mainly transported in the blood via triglyceride-rich lipoproteins whereas low-density lipoproteins transport MK-7.
The daily requirement of MK-7 is much lower compared to MK-4 (around 90-120 μg/day for MK-7 and 45,000 μg three times a day for MK-4.)
Technical insights:
- Country of origin: Denmark
- Starting material: Pharmaceutical synthesis vitamin K2 from geriniol
- Trans isomer
Corn Allergen
Coconut Allergen
Non-GMO
Ingredient Benefits
Helps bones use calcium more effectively
The most popular, albeit recently highlighted, use for vitamin K2 is for bone health. Vitamin K2 along with vitamin D is essential for proper calcium absorption and usage in the bones. Vitamin K2 also stimulates the synthesis of proteins that regulate bone growth and has been shown to reduce the incidence of osteoporotic fractures and improve bone quality.
Supports heart health
Vitamin K is also essential to cardiovascular health. By the same token, vitamin K enhances calcium absorption from the bloodstream into the bones, preventing arterial calcification and promoting healthy blood vessel function and heart health.
Vitamin K2 MK-7 exists in two isomeric forms – cis and trans. The trans isomer is the naturally occurring and the most bioactive form of MK-7. All trans MK-7 is linear in structure due to an extended system of isoprenoid units whereas the cis isomers are non-linear. Hence, the cis MK-7 does not fit well into subcellular structures, leaving K2-dependent enzymes and proteins inactivated.
Fermentation-derived vitamin K2 MK-7 is usually a mixture of trans and cis isomers along with other compounds. Trans MK-7 must be purified from this mixture to obtain the bioactive substance. Synthetic K2 MK-7, on the other hand, bypasses these issues as the final product obtained is all trans K2 MK-7 with no contamination from cis isomers or other compounds.
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