CurcuVIVA™

AOR04257

Highly absorbable and effective curcumin formula

  • Allows slow breakdown by the body
  • Mild dose-optimized curcumin from turmeric
  • Remains in the bloodstream for up to 24 hours
Gluten Free
Non-GMO
Vegan

$49.95 or subscribe and save 20%

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CurcuVIVA™ provides an 80 mg maintenance dose of Longvida Optimized Curcumin for those with osteoarthritis, joint pain, chronic pain and more. Longvida Curcumin was specially formulated to provide a solution to the curcumin conundrum of low bioavailability, poor absorption and rapid breakdown. Although bioavailability and absorption help determine effectiveness, the key lies within its ability to remain free. This free state of curcumin is achieved due to the formula’s ability to avoid being rapidly broken down within the body. Because free curcumin retains its “unbroken” form, it is then taken up through the lymph system into the bloodstream where it is stable, concentrated, and retains maximum effectiveness for up to 24 hours.

Curcumin not only provides relief from joint pain and arthritis, but has many other benefits. It supports digestion, liver and gallbladder health, carries antibacterial, antifungal and antiviral effects, and even promotes healthy cholesterol levels and cardiovascular health.

AOR Advantage

AOR’s CurcuVIVA™ advanced technology allows it to be absorbed very rapidly by the body, meaning that it is an excellent choice for rapid pain relief. Furthermore, with an effective dose of just one capsule per day CurcuVIVA™ is  convenient and  economical.

 

NPN

80034713

Discussion

CurcuVIVA™ contains Longvida®, a highly effective curcumin formula that supports joint health.*

Guarantees

AOR™ guarantees that all ingredients have been declared on the label. Made without wheat, gluten, nuts, peanuts, dairy, eggs, fish, shellfish or any animal by-product.

Adult Dosage

Take one capsule per day with/without food, or as directed by a qualified health care practitioner.

Cautions

Consult your health care practitioner prior to use if you are pregnant, lactating, or taking any medication ( e.g. antiplatelet medications or blood thinners), or have a medical condition ( e.g. have stomach ulcers, excess stomach acid, gallstones, or a bile duct obstruction). Keep out of reach of children.

Main Applications
  • Antioxidant
  • Immune health support
  • Cognitive support
  • Cellular growth and differentiation
  • Lipid metabolism
  • Gastrointestinal health
Disclaimer

The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide or replace medical advice to individuals from a qualified health care professional. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

Serving Size: One Capsule
Longvida® Optimized Curcumin* (from Curcuma longa root)
80 mg

*LONGVIDA® is a registered trademark of Verdure Sciences Inc. International patent pending.

Non-medicinal Ingredients: ascorbyl palmitate, soy lecithin, maltodextrin, microcrystalline cellulose, silicon dioxide, stearic acid, sodium stearyl fumarate. Capsule: hypromellose.

Contains: Soy.

Alleviates Pain and Symptoms of Arthritis

Patients between the ages of 40 and 65 years with diagnosed osteoarthritis of the knee were given either 160mg of LongvidaÒ curcumin, or a combination of 400mg ibuprofen and a placebo tablet, for 90 days. From day 45 of treatment onwards, there was significant improvement in visual analogue scale (VAS) scores in both treatment groups. Reduction in pain was significant by two months of treatment in both groups compared to baseline, and no difference was seen between the groups. This illustrates that LongvidaÒ curcumin was as effective as ibuprofen in reducing osteoarthritic pain.

Gupte PA, Giramkar SA, Harke SM, et al. (2019). Evaluation of the efficacy and safety of capsule LongvidaÒ optimized curcumin (solid lipid curcumin particles) in knee osteoarthritis: a pilot clinical study. J Inflamm Res. 12:145-52

 

Improves Cognition and Mood in the Middle-aged and Elderly Subjects

Study #1:
In a randomized, double-blind placebo-controlled study, the effect of both acute (one hour and three hours post-dosing) and chronic (four weeks) use of 400mg daily LongvidaÒ curcumin on cognitive function and mood was tested in 60 healthy elderly subjects aged 60-85 years. In the acute trials, subjects given LongvidaÒ curcumin had significantly improved performance on sustained attention and working memory tasks, compared to the placebo group, one hour after administration. After chronic treatment, subjects again had a significantly improved working memory and mood (as measured by fatigue, calmness, and a sense of psychological stress).

Cox KHM, Pipingas A, Scholey AB. (2015). Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population. J Psychopharmacol. 29(5): 642-51

Study #2:

In a double-blind, placebo-controlled parallel groups trial, 80 subjects aged 50 to 80 years were randomized to either 400 mg LongvidaÒ (containing 80 mg SLCP curcumin) or placebo for 12 weeks. The group given curcumin had significantly better working memory and lower fatigue scores after four and 12 weeks of treatment compared to the placebo group. Additionally, at the four week mark (but not at 12 weeks), the curcumin group reported significant decreases in mood disturbances (including anxiety, tension, confusion and anger) compared to placebo.

Cox KHM, White DJ, Pipingas A, et al. (2020). Further evidence of benefits to mood and working memory from lapidated curcumin in healthy older people: a 12-week, double-blind, placebo-controlled, partial replication study. Nutrients. 12(6): 1678

 

Decreases LDL Cholesterol and the Risk for Atherosclerosis and Cardiovascular Disease

Study #1:

In a randomized, double blind, placebo controlled study, 60 healthy elderly subjects aged 60-85 years were given 400 mg of LongvidaÒ curcumin daily for four weeks. In addition to improved cognitive function, researchers also noted a significant reduction in total and LDL cholesterol.

Cox KHM, Pipingas A, Scholey AB. (2015). Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population. J Psychopharmacol. 29(5): 642-51

Study #2:

A small placebo-controlled study examined the effect of 80mg per day of Longvida curcumin in 36 healthy adults aged 40 to 60 years. After four weeks of treatment, several blood markers had changed significantly: lower triglyceride levels, increased antioxidant capacity, lower concentrations of beta-amyloid (associated with the brain plaques found in Alzheimer’s disease), and decreased markers of atherosclerosis.

DiSilvestro RA, Joseph E, Zhao S and Bomser J. (2012). Diverse effects of a low dose supplement of lapidated curcumin in healthy middle aged people. Nutr J. 11:79

 

Anti-amyloid and Anti-inflammatory Neuroprotective Effects

Study #1:

In a study with both in vitro and in vivo models of Alzheimer’s disease (AD), the effects of untreated curcumin were compared with SLCP (Longvida) curcumin. In the animal model of AD, SLCP was able to permeate brain tissue more effectively than plain curcumin. Five days of SLCP treatment led to a greater decrease in the tangle-like neurons of the hippocampus. Researchers also measured other markers (GFAP-IR, Iba-1-IR, and others) associated with amyloid plaques and concluded that SLCP provided greater neuroprotection and anti-amyloid effects compared to untreated curcumin powder.

Maiti P, Paladugu L, Dunbar GL. (2010). Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer’s disease. BMC Neurosci. 19(1): 7

Study #2:

In an animal study of cognitive decline, Longvida curcumin was fed to mice with compromised cognitive and motor function (GFAP-IL6 mice) for six months. Feeding mice the Longvida curcumin led to significant decreases (26%) in Iba-1+ mircoglia in the hippocampus and in the cerebellum (31%). As well, microglia dendrite length decreased and pre- and post-synaptic protein levels increased after curcumin feeding. This suggests that Longvida curcumin can attenuate inflammation and decrease neurodegeneration in GFAP-IL6 mice.

Ullah F, Asgarov R, Venigalla M, et al. (2020). Effects of a solid lipid curcumin particle formulation on chronic activation of microglia and astroglia in the GFAP-IL6 mouse model. Sci Rep. 10(1): 2365

Study #3:

Included in the tau pathology and amyloid-beta plaque formation pathology of AD is the deregulation of the activity of the enzyme cyclin-dependent kinase 5 (Cdk5). Hyperactive p25/Cdk5 is associated with significant neuroinflammation. In this study, researchers used an animal model of this state (p25Tg mice). When treated with curcumin, p25-mediated glial activation and pro-inflammatory cytokine production was attenuated. By supressing this neuroinflammation there was a decrease in the progression of the tau and amyloid pathology induced by p25, thereby reducing cognitive impairment.

Dundaram JR, Poore CP, Sulaimee NHB, et al. (2017). Curcumin ameliorates neuroinflammation, neurodegeneration, and memory deficits in p25 transgenic mouse model that bears hallmarks of Alzheimer’s disease. J Alzheimer’s Dis. 60(4): 1429-42