The Effects of a Saffron Extract (Affron®) on Menopausal Symptoms in Women during Perimenopause: A Randomised, Double-Blind, Placebo-Controlled Study

The aim of this 2021, 12-week, parallel-group, double-blind, randomised controlled trial, was to examine the tolerability and efficacy of a standardised saffron extract (Affron®) on menopausal complaints in perimenopausal women. 86 perimenopausal women experiencing menopausal complaints received either a placebo or 14 mg of a saffron extract (affron®), twice daily. Results found a 33% reduction in anxiety and a 32% reduction in depression scores from baseline to week 12. There was also a significantly greater reduction in the PANAS negative affect score (P = 0.043) compared to the placebo.

INGREDIENTS WITH THIS RESEARCH​

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