benaGene ™ Oxaloacetate, oxaloactic acid, 3-carboxy-3-oxopropanoic acid
AOR was the first to introduce to North America a stable and bioavailable oxaloacetic acid in benaGene®.
The body naturally makes oxaloacetic acid as an important factor in metabolism and a key in the citric acid cycle (also known as the Krebs cycle). It is the sequence of reactions that creates energy for most living cells. The end product is ATP, which is the most usable form of energy.
There has been a reasonable amount of research conducted on the key benaGene® ingredient, oxaloacetate. Both experimental and clinical studies have been used to investigate oxaloacetic acid for its antioxidant effects. Most of the research done in the last seven years have been reviews, along with a few clinical or experimental studies.
Technical insights:
- Country of origin: Hungary
- Thermally stabilized along with vitamin C for superior stability and shelf life
Ingredient Benefits
Neuroprotection For the Brain
Oxaloacetate has been shown to play a role in protecting brain function in part by scavenging glutamate in the blood. One of the most common signs of aging is an increase in neurotoxicity. This function of oxaloacetate essentially helps to protect brain neurons from neurotoxicity, also known as glutamatergic excitotoxicity.
Healthy Aging
Oxaloacetate helps support healthy aging by protecting the brain from the onset of dementia. Neurotoxicity can have devastating effects on the brain’s ability to remember things that happened both in the far distant past and in the recent past by offering protection to the brain’s neurons. Of course, neurons are how the brain communicates to various areas of the brain as well as to the body. This communication flow is at least partially protected by oxaloacetate.
Cellular Longevity
Caloric restriction is the only method proven to extend human lifespan and health span. benaGene® is a novel caloric restriction mimetic (CR mimetic), mimicking up to 98% of the changes in the genetic expression of over 350 genes in a similar fashion to caloric restriction. This is exciting news, since calorie restriction also offers an abundance of other health benefits, such as better cholesterol levels, reduction in high blood pressure, enhanced blood sugar control, and a return to normal insulin production levels.
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