I-3-C

Promotes healthy estrogen metabolism

Product Highlights

  • A phytonutrient found in broccoli
  • Antioxidant support to help protect against cell damage caused by free radicals
  • An effective dose of I3Cper capsule

$44.84
$0.75 per capsule

$41.70 each in cart with 7% off orders over $25

Size: 60 capsules

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Product Information

Details

Indole-3-carbinol (I-3-C) is a phytonutrient found in Brassica vegetables such as broccoli, kale and cabbage, and is one of the key health-promoting compounds in these foods.

To understand benefits we must first consider estrogen. “Estrogen” is actually not one substance, but a family of forms: E1, E2, and E3 that stimulate the growth and development of women’s reproductive systems. These forms all undergo metabolism in the liver which can yield different end products or metabolites. The estrogen metabolite 16 alpha-hydroxyestrone (16OHE) is a “bad” estrogen as it can increase risk of damaging cells. On the other hand, “good” estrogens also exist, in the form of 2-hydroxyestrone (2OHE), along with 2-methoxyestradiol. The idea is to encourage the body to favour detoxification into these less harmful pathways and then ensure proper packaging and excretion of these “old” hormones.

Human studies in women taking I-3-C have shown a favourable shift in estrogen metabolism.

AOR Advantage

AOR’s I-3-C provides a safe and effective dose of this natural ingredient.

I3C vs DIM

I3C needs stomach acid to then convert into 15+ compounds, of which the most predominant is DIM. While there are advantages for supplementing with DIM directly (in individuals with poor stomach acid conversion), some may want to take this parent molecule for the synergy of the other compounds produced. 

Label Information

NPN

80023077

Adult Dosage

Adults (18 years and over) – Take 1 capsule one to two times daily with or without food, or as directed by a qualified health care practitioner. Do not crush, mix or blend capsules. Swallow capsules whole. Do not exceed daily dose unless instructed by a healthcare practitioner.

Cautions

Do not use if you are pregnant or breastfeeding.                                                                                                                            

Consult a health care practitioner before use:

  • to exclude the diagnosis of a serious cause of hormonal imbalance
  • if you are taking any medications or natural health products
  • if you are attempting to conceive
  • (For female subpopulation): if you have a liver disorder or symptoms of low estrogen such as joint pain, mood changes, changes in libido, hot flashes, night sweats, vaginal dryness or irregular menstruations.
  • (For male subpopulation): if you have a liver disorder or symptoms of low estrogen such as joint pain, mood changes or changes in libido.

Stop use and ask a health care practitioner if you develop liver-related symptoms (e.g., abdominal pain, jaundice) or symptoms of low estrogen.

Supplement Facts

Supplement Facts
Medicinal ingredientPer one capsuleDaily dose, up to two capsules
Indole-3-Carbinol (I3C)200 mg400 mg
  • Indole-3-Carbinol (I3C)Per one capsule 200 mg Max Daily 400 mg

Non-medicinal Ingredients*: microcrystalline cellulose. Capsule: hypromellose.

*NMIs are subject to change. Always read and follow the label for accurate ingredient and allergen information.

Disclaimer

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Pairs well with

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