Research Category: Preclinical
In a 2019 study in rats comparing several magnesium supplements, the researchers found that magnesium malate provided the most bioavailable magnesium. Five different magnesium compounds (magnesium sulfate, magnesium oxide, magnesium acetyl taurate, magnesium citrate and magnesium malate) were administered as a single dose 400 mg/70 kg to Sprague Dawley rats. Bioavailability was evaluated by examining […]
From 2004 this pharmacokinetic study examined Fe absorption of micronized, dispersible ferric pyrophosphate with that of ferrous sulfate in an infant cereal and a yogurt drink. While absorption was not different between the two forms, the bioavailability of SunActive was high indicating it may be better for iron fortification. References: Fidler, M. C., Walczyk, T., […]
This preclinical review from 2023 provides insights into how lactic acid in the gut can transform soy isoflavones and their impact on health. Many lactic acid bacteria (LAB) can transform the methylated and glycosylated forms of isoflavones naturally present in foods into more bioavailable aglycones, such as daidzein, genistein and glycitein. References: Rietjens IMCM, Louisse […]
Early use of adrenal extract was conducted in the 1930’s in clinical settings, whereby much of the regulatory framework which banned active hormone use was likely not in place. Since then there has not been as rigorous investigation as one would like with new preparations of both whole extract and cortex. However, in 1985 French […]
This review from 2017 assessed the relationship between biotin supplementation and hair loss. With 18 studies reviewed the authors found that while biotin supplementation was effective, it was only shown to be helpful if an underlying biotin deficiency was established. References: Patel DP, Swink SM, Castelo-Soccio L. A Review of the Use of Biotin for […]
