Research Category: RCT
From 2016 this randomized, double-blinded, placebo-controlled study investigated the effect of 90-day supplementation of a standardized extract of fenugreek (Trigonella foenum-graecum) (FenuSMART™), at a dose of 1000 mg/day, on plasma estrogens and postmenopausal discomforts. Eighty-eight women having moderate to severe postmenopausal discomforts were randomized either to extract-treated (n = 44) or placebo (n = 44) […]
From 2017 this double-blind, randomized, placebo-controlled trial, aimed to assess efficacy of a standardized T. foenum-graecum de-husked seed extract in reducing menopausal symptoms in healthy aging women. 115 women aged 40 to 65 years of which 59 were allocated to active (n = 54 completed) and 56 to placebo (n = 50 completed). Active treatment […]
From 2020 this was a 28-day, parallel-group, double-blind, randomized controlled trial. Sixty-three healthy adults aged 18–70 with self-reported sleep problems were recruited. The intervention group were randomized to receive either saffron extract (affron; 14 mg twice daily) or a placebo. Saffron was associated with greater improvements in ISI total score (P = .017), RSQ total […]
The aim of this 2021, 12-week, parallel-group, double-blind, randomised controlled trial, was to examine the tolerability and efficacy of a standardised saffron extract (Affron®) on menopausal complaints in perimenopausal women. 86 perimenopausal women experiencing menopausal complaints received either a placebo or 14 mg of a saffron extract (affron®), twice daily. Results found a 33% reduction […]
This randomized, double-blind, placebo-controlled clinical study from 2015 showed that MS patients receiving 500 mg/day of CoQ10 for 12 weeks presented with a significant decrease of inflammatory cytokine. CoQ10 also alleviates markers of CNS inflammation. References: Sanoobar M, Eghtesadi S, Azimi A, Khalili M, Khodadadi B, Jazayeri S, Gohari MR, Aryaeian N. Coenzyme Q10 supplementation […]
In a randomized, double-blind controlled trial from 2015, 30 overweight or obese participants were given either 250 mg C. forskohlii extract or placebo twice daily for 12 weeks. Participants in both groups were to follow a hypocaloric diet throughout the study. At the end of the study both groups had significant reductions in hip and […]
In a double-blind, placebo-controlled trial from 2018, 53 women aged 40-60 years were randomized to receive 1000 mg of low-molecular weight collagen peptide supplement (a fish-derived collagen hydrolysate) or placebo, daily for 12 weeks. The group given collagen had significantly higher values of skin-hydration after 6 weeks and 12 weeks. Several parameters of skin elasticity […]
In a double-blind, placebo-controlled study from 2014, 114 women aged 45-65 years were randomized to receive 2.5 g of a collagen peptide supplementation or placebo daily for eight weeks. Eye wrinkles were visibly and significantly reduced in the group given collagen (p<0.05) at 4 weeks and 8 weeks. Researchers also detected a significantly higher content […]
Following 12 weeks of supplementation, this randomized double blind placebo controlled trial had 98 subjects with high cholesterol. There was a significant decrease in total cholesterol, triglycerides, LDL-cholesterol and VLDL cholesterol levels in the amla supplementation group, compared to the placebo group. References: Upadya, H., Prabhu, S., Prasad, A., Subramanian, D., Gupta, S., & Goel, […]
In this randomized, placebo-controlled clinical study, the effect of milk basic protein on bone mineral density (BMD) and bone density was evaluated in young women. The results showed an increase in BMD in all groups, compared to the baseline, with both milk and MBP groups showing a larger increase in BMD. Bone metabolism was also […]
