Research Category: Health Conditions
From 2016 this randomized, double-blinded, placebo-controlled study investigated the effect of 90-day supplementation of a standardized extract of fenugreek (Trigonella foenum-graecum) (FenuSMART™), at a dose of 1000 mg/day, on plasma estrogens and postmenopausal discomforts. Eighty-eight women having moderate to severe postmenopausal discomforts were randomized either to extract-treated (n = 44) or placebo (n = 44) […]
In a 2021 review authors outlined preclinical and clinical evidence around fenugreek seeds impacts on numerous diseases including: cholesterol, reducing cardiovascular risk, controlling diabetes, skin infection, milk production, reduce menstrual discomfort, and reducing vasomotor symptoms during menopause.
From 2017 this double-blind, randomized, placebo-controlled trial, aimed to assess efficacy of a standardized T. foenum-graecum de-husked seed extract in reducing menopausal symptoms in healthy aging women. 115 women aged 40 to 65 years of which 59 were allocated to active (n = 54 completed) and 56 to placebo (n = 50 completed). Active treatment […]
From 2020 this was a 28-day, parallel-group, double-blind, randomized controlled trial. Sixty-three healthy adults aged 18–70 with self-reported sleep problems were recruited. The intervention group were randomized to receive either saffron extract (affron; 14 mg twice daily) or a placebo. Saffron was associated with greater improvements in ISI total score (P = .017), RSQ total […]
The aim of this 2021, 12-week, parallel-group, double-blind, randomised controlled trial, was to examine the tolerability and efficacy of a standardised saffron extract (Affron®) on menopausal complaints in perimenopausal women. 86 perimenopausal women experiencing menopausal complaints received either a placebo or 14 mg of a saffron extract (affron®), twice daily. Results found a 33% reduction […]
To determine the effects of BCAA supplementation on fatigue, muscle damage and energy metabolism after endurance exercise, this randomized, double-blind, placebo-controlled clinical trial from 2013 was carried out. These results suggest that BCAA may reduce muscle damage associated with endurance exercise.
This review from 2020 included 11 eligible studies evaluating the effectiveness of boron supplementation (alone or with other micronutrients) on growth and maintenance of bone in humans through control of calcium, vitamin D and sex steroid hormone metabolism. Authors concluded supplementation of 3 mg / day is considered useful to support bone health (in order to […]
This review from 2016 focused on traditional uses, phytochemistry, pharmacology and toxicology of Boerhavia genus to support potential scope for advanced ethnopharmacological study. 180 compounds from Boerhavia genus were isolated, of which B. diffusa alone, shared around 131 compounds and for most of which it is currently an exclusive source. References: Patil, K. S., & […]
This comprehensive review published in 2021 evaluated evidence relating to the clinical use of exogenous supplemental bovine colostrum in human health. 24 full text studies were selected and reviewed regarding intestinal and respiratory recovery. The mechanism of action seemed to suggest bovine colostrum modulates the immune response and may increase sIgA. References: Guberti, M., Botti, […]
This comprehensive review published in 2021 in Nutrients, reviews the main constituents, quality control and an overview of the use of bovine colostrum in health and disease. Bovine colostrum active constituents include immunoglobulins, cytokines, oligosaccharides and immune factors. It also contains growth factors and hormones which account for many of the health benefits. Multiple studies […]
