Research Category: Health Conditions

The use of bovine colostrum in medical practice and human health: Current evidence and areas requiring further examination 

The prestigious scientific journal Nutrients published this special edition in 2022 for a comprehensive review of the health potential of bovine colostrum supplementation.   Including five review articles, use in gastrointestinal health and disease, sports nutrition, pediatrics, and immune support. It also includes a systematic review of its clinical use and an original research article examining […]

Calcium supplementation in clinical practice: A review of forms, doses and indications 

This review from 2007 is the only comprehensive assessment of the various types of calcium salt forms. Suggesting that calcium carbonate offers an effective and cost-efficient form that should be taken with a meal to ensure optimal absorption.  References: Straub DA. Calcium supplementation in clinical practice: a review of forms, doses, and indications. Nutr Clin […]

Calcium D Glucarate Monograph for Detoxification 

This monograph from 2007 provides a review of available evidence for the therapeutic uses of calcium D glucarate. Through suppression of beta glucuronidase activity, hormone and lipid excretion can occur as normal making this particularly useful in excess conditions.  References: Calcium-D-glucarate. Altern Med Rev. 2002;7(4):336‐339. https://pubmed.ncbi.nlm.nih.gov/12197785/ 

Phytate intake, health and disease: “Let thy food be thy medicine and medicine be thy food” 

From 2023, this comprehensive review examines health benefits of phytates and related research. “Phytate has a potent antioxidation and anti-inflammatory action. It is capable of inhibiting lipid peroxidation through iron chelation, reducing iron-related free radical generation. As this has the effect of mitigating neuronal damage and loss, phytate shows promise in the treatment/prevention of neurodegenerative […]

Calcium supplementation in clinical practice: A review of forms, doses and indications 

This review from 2007 is the only comprehensive assessment of the various types of calcium salt forms. Suggesting that calcium citrate can be taken without food and is the supplement of choice for individuals with achlorhydria or who are taking histamine-2 blockers or protein-pump inhibitors.  References: Straub DA. Calcium supplementation in clinical practice: a review of […]

Choline supplements: An update 

From 2023, this review of supplemental forms of choline currently available includes choline alfoscerate also known as alpha-glycerophosphocholine (α-GPC or GPC), choline bitartrate, lecithin and citicoline. One of the most used is choline bitartrate, which has shown favorable effects both in preclinical and clinical studies, especially in terms of improved cognitive function.  References: Kansakar U, […]

Chondroprotection and the prevention of osteoarthritis progression of the knee: a systematic review of treatment agents. 

A study published in the American Journal of Sports Medicine in 2014 consisting of a systematic review of 13 randomized controlled trials evaluated the effectiveness of 12 different agents in preserving articular cartilage of the knee and delaying the progression of osteoarthritis. Treatment with chondroitin sulfate showed a significant reduction in cartilage loss in three […]

Update on the role of pharmaceutical-grade chondroitin sulfate (CS) in the symptomatic management of knee osteoarthritis. 

In this literature review from 2019, the authors summarized the most recent findings on the efficacy and safety of CS in OA.  Based on the results of studies presenting a low risk of bias, the most recent meta-analysis shows that only the pharmaceutical-grade CS may be considered as an appropriate background treatment for the management […]

Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: A meta-analysis of randomized controlled trials 

A meta-analysis of randomized controlled trials published in the Journal of Orthopaedics Surgery and Research in 2018 assessed the symptomatic effectiveness and safety of oral symptomatic slow-acting drugs (SYSADOAs) on the treatment of knee and/or hip osteoarthritis, such as chondroitin, glucosamine, and combination treatment with chondroitin plus glucosamine. Twenty-six articles describing 30 trials met the […]

Cinnamon intake lowers fasting blood glucose: meta-analysis. 

This meta-analysis from 2011 assessed the effects of cinnamon extracts on blood glucose in patients with type 2 diabetes and/or prediabetes. Eight clinical studies designed as randomized, placebo-controlled trials were included. Authors concluded that results of the eight studies demonstrated statistically significant benefits for type 2 diabetics or prediabetics for lowering their blood glucose. References: […]

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