Research Category: Review

Fenugreek Cultivation with Emphasis on Historical Aspects and its uses in Traditional Medicine and Modern Pharmaceutical Science

In a 2021 review authors outlined preclinical and clinical evidence around fenugreek seeds impacts on numerous diseases including: cholesterol, reducing cardiovascular risk, controlling diabetes, skin infection, milk production, reduce menstrual discomfort, and reducing vasomotor symptoms during menopause.

Pivotal role of boron supplementation on bone health: A narrative review 

This review from 2020 included 11 eligible studies evaluating the effectiveness of boron supplementation (alone or with other micronutrients) on growth and maintenance of bone in humans through control of calcium, vitamin D and sex steroid hormone metabolism. Authors concluded supplementation of 3 mg / day is considered useful to support bone health (in order to […]

Ethnomedicinal uses, phytochemistry and pharmacological properties of the genus Boerhavia 

This review from 2016 focused on traditional uses, phytochemistry, pharmacology and toxicology of Boerhavia genus to support potential scope for advanced ethnopharmacological study. 180 compounds from Boerhavia genus were isolated, of which B. diffusa alone, shared around 131 compounds and for most of which it is currently an exclusive source.  References: Patil, K. S., & […]

Bovine colostrum applications in sick and healthy people: A systematic review 

This comprehensive review published in 2021 evaluated evidence relating to the clinical use of exogenous supplemental bovine colostrum in human health. 24 full text studies were selected and reviewed regarding intestinal and respiratory recovery. The mechanism of action seemed to suggest bovine colostrum modulates the immune response and may increase sIgA.   References: Guberti, M., Botti, […]

Bovine colostrum: Its constituents and uses 

This comprehensive review published in 2021 in Nutrients, reviews the main constituents, quality control and an overview of the use of bovine colostrum in health and disease.   Bovine colostrum active constituents include immunoglobulins, cytokines, oligosaccharides and immune factors. It also contains growth factors and hormones which account for many of the health benefits. Multiple studies […]

The use of bovine colostrum in medical practice and human health: Current evidence and areas requiring further examination 

The prestigious scientific journal Nutrients published this special edition in 2022 for a comprehensive review of the health potential of bovine colostrum supplementation.   Including five review articles, use in gastrointestinal health and disease, sports nutrition, pediatrics, and immune support. It also includes a systematic review of its clinical use and an original research article examining […]

Calcium supplementation in clinical practice: A review of forms, doses and indications 

This review from 2007 is the only comprehensive assessment of the various types of calcium salt forms. Suggesting that calcium carbonate offers an effective and cost-efficient form that should be taken with a meal to ensure optimal absorption.  References: Straub DA. Calcium supplementation in clinical practice: a review of forms, doses, and indications. Nutr Clin […]

Calcium D Glucarate Monograph for Detoxification 

This monograph from 2007 provides a review of available evidence for the therapeutic uses of calcium D glucarate. Through suppression of beta glucuronidase activity, hormone and lipid excretion can occur as normal making this particularly useful in excess conditions.  References: Calcium-D-glucarate. Altern Med Rev. 2002;7(4):336‐339. https://pubmed.ncbi.nlm.nih.gov/12197785/ 

Phytate intake, health and disease: “Let thy food be thy medicine and medicine be thy food” 

From 2023, this comprehensive review examines health benefits of phytates and related research. “Phytate has a potent antioxidation and anti-inflammatory action. It is capable of inhibiting lipid peroxidation through iron chelation, reducing iron-related free radical generation. As this has the effect of mitigating neuronal damage and loss, phytate shows promise in the treatment/prevention of neurodegenerative […]

Choline supplements: An update 

From 2023, this review of supplemental forms of choline currently available includes choline alfoscerate also known as alpha-glycerophosphocholine (α-GPC or GPC), choline bitartrate, lecithin and citicoline. One of the most used is choline bitartrate, which has shown favorable effects both in preclinical and clinical studies, especially in terms of improved cognitive function.  References: Kansakar U, […]

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